WALTHAM, Mass., July  14, 2026  (GLOBE NEWSWIRE) -- Crescent Biopharma, Inc. (&#34;Crescent&#34; or the &#34;Company&#34;) (NASDAQ:CBIO), a clinical-stage biotechnology company dedicated to rapidly advancing the next

CBIO

Crescent Biopharma Announces Proposed Public Offering of Ordinary Shares and Pre-Funded Warrants

Crescent Biopharma launches public offering; CBIO dilution risk ahead

<section class="insight" data-version="1">
  <section data-block="information">
    <h3>Information</h3>
    <p>WALTHAM, Mass., July  14, 2026  (GLOBE NEWSWIRE) -- Crescent Biopharma, Inc. (&amp;#34;Crescent&amp;#34; or the &amp;#34;Company&amp;#34;) (NASDAQ:CBIO), a clinical-stage biotechnology company dedicated to rapidly advancing the next</p>
  </section>

  <section data-block="ai-summary-paragraph">
    <h3>AI Summary</h3>
    <p>Crescent Biopharma announced an underwritten public offering of ordinary shares or pre-funded warrants, with a 30-day option to purchase up to 15% more. The deal could raise cash but may dilute existing shareholders and pressure CBIO stock in the near term; proceeds would support its PD-1 x VEGF bispecific program and ADC development.</p>
  </section>

  <section data-block="ai-summary-bullets">
    <h3>Key Points</h3>
    <ul><li>Crescent Biopharma initiates underwritten public offering of ordinary shares or pre-funded warrants.</li><li>Underwriters Jefferies, TD Cowen, Guggenheim, Cantor; 30-day option for 15% more.</li><li>Shelf registration on Form S-3 effective July 10, 2026; prospectus to follow.</li><li>Offering subject to market conditions and closing risk; size unknown.</li><li>Background: Crescent&#039;s lead PD-1 x VEGF bispecific and ADCs in pipeline.</li></ul>
  </section>

  <section data-block="companies-mentioned">
    <h3>Companies Mentioned</h3>
    <ul><li><strong>Crescent Biopharma (CBIO)</strong>: Issuer of the offering; primary market impact will be dilution risk.</li><li><strong>Jefferies LLC (JEF)</strong>: Joint book-running manager; high credibility; underwriter involvement supports potential size.</li><li><strong>TD Cowen (TD)</strong>: Joint book-running manager; part of underwriting syndicate.</li><li><strong>Guggenheim Securities (N/A)</strong>: Joint book-running manager; private firm, no ticker provided.</li><li><strong>Cantor Fitzgerald &amp; Co. (N/A)</strong>: Joint book-running manager; private firm.</li><li><strong>LifeSci Capital LLC (N/A)</strong>: Passive book-running manager; private broker-dealer.</li></ul>
  </section>

  <section data-block="category">
    <h3>Corporate Developments</h3>
    <p>The article fits Corporate Developments, focusing on a financing event that could affect CBIO&#039;s liquidity and share count.</p>
  </section>

  <section data-block="market-moving">
    <h3>Market-Moving</h3>
    <ul><li>Public offering triggers near-term dilution concerns for CBIO.</li><li>30-day option for 15% more shares expands potential equity overhang.</li><li>Top-tier banks named as underwriters suggest a sizable offering.</li><li>Shelf registration effective July 10, 2026; pricing not disclosed yet.</li></ul>
  </section>

  <section data-block="key-facts">
    <h3>Key Facts</h3>
    <ul><li>Date: July 14, 2026</li><li>Ticker: CBIO</li><li>Offering: ordinary shares or pre-funded warrants; underwritten public offering</li><li>Underwriters: Jefferies, TD Cowen, Guggenheim Securities, Cantor Fitzgerald; LifeSci Capital as passive manager</li><li>Over-allotment option: 30 days to purchase up to 15% more shares</li><li>Shelf registration: Form S-3 effective July 10, 2026</li><li>Completion is subject to market conditions; not guaranteed</li></ul>
  </section>

  <section data-block="trading-thesis">
    <h3>Trading Thesis</h3>
    <p>Near-term CBIO is exposed to dilution-driven downside; potential rebound if pricing is favorable and demand materializes within weeks.</p>
  </section>
</section>


<link type="text/css" rel="stylesheet" href="https://www.globenewswire.com/styles/gnw_nitf.css"></link><p align="left">WALTHAM, Mass., July  14, 2026  (GLOBE NEWSWIRE) -- Crescent Biopharma, Inc. ("Crescent" or the "Company") (NASDAQ:<a class="ticker" href="https://www.benzinga.com/quote/CBIO">CBIO</a>), a clinical-stage biotechnology company dedicated to rapidly advancing the next wave of therapies for cancer patients, today announced that it has commenced an underwritten public offering of its ordinary shares or, in lieu of ordinary shares to investors that so choose, pre-funded warrants to purchase its ordinary shares. In addition, Crescent intends to grant the underwriters a 30-day option to purchase up to an additional 15% of the ordinary shares at the public offering price, less underwriting discounts and commissions. All of the ordinary shares and pre-funded warrants to be sold in the proposed offering are being offered by Crescent. The proposed offering is subject to market and other conditions, and there can be no assurance as to whether or when the proposed offering may be completed, or as to the actual size or terms of the proposed offering.</p>  <p align="left">Jefferies, TD Cowen, Guggenheim Securities and Cantor are acting as joint book-running managers for the proposed offering. LifeSci Capital is acting as passive book-running manager for the proposed offering.</p>  <p align="left">The securities described above are being offered by Crescent pursuant to a shelf registration statement on Form S-3, including a base prospectus, that was previously filed with the Securities and Exchange Commission ("SEC") and was declared effective on July 10, 2026. A preliminary prospectus supplement and accompanying prospectus relating to this offering will be filed with the SEC. Copies of the preliminary prospectus supplement and accompanying prospectus can be accessed through the SEC’s website at www.sec.gov. Copies of the prospectus supplement relating to the proposed offering may be obtained, when available, by contacting Jefferies LLC, Attention: Equity Syndicate Prospectus Department, 520 Madison Avenue, New York, NY 10022, by telephone at (877) 821-7388, or by email at Prospectus_Department@Jefferies.com; TD Securities (USA) LLC, c/o Broadridge Financial Solutions, 1155 Long Island Avenue, Edgewood, NY 11717, or by email at TDManualrequest@broadridge.com; Guggenheim Securities, LLC, Attention: Equity Syndicate Department, 330 Madison Avenue, 8th Floor, New York, NY 10017, by telephone at (212) 518-9544, or by email at GSEquityProspectusDelivery@guggenheimpartners.com; Cantor Fitzgerald &amp; Co., Attention: Capital Markets, 110 East 59th Street, 6th Floor, New York, NY 10022, or by email at prospectus@cantor.com; and LifeSci Capital LLC, Attention: LifeSci Capital LLC, 1700 Broadway, 40th Floor, New York, NY 10019, or by email at legalnotices@lifescicapital.com.</p>  <p align="left">This press release shall not constitute an offer to sell or the solicitation of an offer to buy these securities, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such state or jurisdiction.</p>  <p align="left"><strong>About Crescent Biopharma</strong></p>  <p align="left">Crescent Biopharma’s vision is to build a world leading oncology company bringing the next wave of therapies for cancer patients. The Company’s clinical-stage pipeline includes its lead program, a PD-1 x VEGF bispecific antibody, as well as novel antibody-drug conjugates (ADCs). By leveraging multiple modalities and established targets, Crescent aims to rapidly advance potentially transformative therapies as single agents and as part of combination regimens to treat a range of solid tumors.</p>  <p align="left"><strong>Forward-Looking Statements</strong></p>  <p align="left">Crescent cautions you that statements contained in this press release regarding matters that are not historical facts are forward-looking statements. The forward-looking statements are based on our current beliefs and expectations and include, but are not limited to: our expectations regarding the completion, timing and size of the proposed offering, and the grant of the option to purchase additional ordinary shares. Actual results may differ from those set forth in this press release due to the risks and uncertainties associated with market conditions and the satisfaction of customary closing conditions related to the proposed offering, as well as risks and uncertainties inherent in our business described in our prior filings with the SEC, including under the heading "Risk Factors" in our annual report on Form 10-K for the year ended December 31, 2025, our quarterly report on Form 10-Q for the quarter ended March 31, 2026, and any subsequent current reports on Form 8-K or other filings with the SEC. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof, and we undertake no obligation to update such statements to reflect events that occur or circumstances that exist after the date hereof. All forward-looking statements are qualified in their entirety by this cautionary statement, which is made under the safe harbor provisions of the Private Securities Litigation Reform Act of 1995.</p>  <p align="left"><strong>Contacts</strong></p>  <p align="left"><strong>Investors</strong></p>  <p align="left">Amy Reilly<br></br>Chief Communications Officer<br></br>amy.reilly@crescentbiopharma.com<br></br>617-465-0586</p>  <p align="left"><strong>Media</strong></p>  <p align="left">Jenna Poist<br></br>Director, Corporate Communications<br></br>jenna.poist@crescentbiopharma.com<br></br>781-671-5019</p> <img alt="" class="__GNW8366DE3E__IMG" src="https://www.globenewswire.com/newsroom/ti?nf=OTc2MjE4MiM3NzA2Mjk2IzIyOTg0ODA="></img> <br></br><img alt="" src="https://ml.globenewswire.com/media/YmYyNzYwOWMtNDkzNy00YTBlLTlmYzItZDQwYjI1ZTgyNmIzLTEzMTAwMzAtMjAyNi0wNy0xNC1lbg==/tiny/Crescent-Biopharma-Inc-.png" referrerpolicy="no-referrer-when-downgrade"></img><p><a href="https://www.globenewswire.com/NewsRoom/AttachmentNg/57dabf2a-90a3-4786-9c39-d1e71cc7707f"><img src="https://ml.globenewswire.com/media/57dabf2a-90a3-4786-9c39-d1e71cc7707f/small/crescent-biopharma-logo-color-png.png" border="0" width="150" height="54" alt="Primary Logo"></img></a></p>

Crescent Biopharma announced an underwritten public offering of ordinary shares or pre-funded warrants, with a 30-day option to purchase up to 15% more. The deal could raise cash but may dilute existing shareholders and pressure CBIO stock in the near term; proceeds would support its PD-1 x VEGF bispecific program and ADC development.

Crescent Biopharma Announces Proposed Public Offering of Ordinary Shares and Pre-Funded Warrants

AI Summary

Sentiment Rationale

Trading Thesis

Market-Moving

Key Facts

Companies Mentioned

Corporate Developments

Related News