1. GSK reported Q4 sales of $10.40 billion, beating analyst expectations. 2. Vaccine sales fell 14%, with Arexvy significantly impacted by low demand. 3. Specialty Medicines grew 14%, primarily driven by HIV and asthma drug sales. 4. GSK plans £2 billion share buyback over 18 months, boosting EPS outlook. 5. Long-term sales outlook raised to over £40 billion by 2031.