Incannex Healthcare Receives Prestigious R&D Award for Obstructive Sleep Apnea Treatment
MELBOURNE, Australia and NEW YORK, Jan. 15, 2026 (GLOBE NEWSWIRE) -- Incannex Healthcare Inc. (Nasdaq: IXHL), a clinical-stage biopharmaceutical company, has been awarded the Research and Development Award in the Respiratory Disorders category at the 2025 Clinical Trials Arena Excellence Awards. This recognition celebrates the company’s groundbreaking work on IHL-42X, an oral fixed-dose combination therapy aimed at treating obstructive sleep apnea (OSA).
Overview of the Clinical Trials Arena Excellence Awards
The Clinical Trials Arena Excellence Awards is a prestigious recognition program powered by GlobalData. It involves an extensive analysis of over one billion datasets yearly to identify and rank the top companies and their achievements across more than 200 countries. Incannex’s honor highlights the relevance and impact of its research-driven approach in addressing unmet needs within the respiratory medicine landscape.
Details on IHL-42X and Its Development
IHL-42X is a pioneering oral treatment combining dronabinol and acetazolamide, specifically designed for adults suffering from moderate-to-severe obstructive sleep apnea. Traditional management approaches typically rely on device-based therapies like positive airway pressure (PAP), which many patients find intolerable or ineffective. Incannex's innovative treatment could provide a non-invasive pharmacologic alternative for those who struggle with such devices.
- Target Group: Adults with moderate-to-severe OSA
- Key Components: Dronabinol and acetazolamide
- Development Status: Late-stage with robust Phase 2 clinical program
The Phase 2 clinical program for IHL-42X has shown promise, integrating polysomnography outcomes and validated patient-reported measures. The encouraging safety and tolerability profile observed supports further development of IHL-42X for chronic use, pending approval.
The Strategic Importance of This Recognition
This award underscores Incannex's commitment to innovative research and development strategies. As highlighted by Joel Latham, President and CEO, “We are honored to be recognized for our science-driven approach with IHL-42X. Obstructive sleep apnea remains a significant unmet medical need, and our goal is to offer an effective, oral therapy supported by clinical evidence.”
Such acknowledgment aligns with the Clinical Trials Arena’s mission to identify companies making substantial contributions in key areas of excellence, including innovation and patient-focused outcomes. It showcases Incannex’s broader pipeline developments, which include:
- IHL-42X: Treatment for obstructive sleep apnea
- IHL-675A: Combination therapy for inflammatory conditions
- PSX-001: Synthetic psilocybin treatment for generalized anxiety disorder
Conclusion and Future Outlook
With the recognition from the Clinical Trials Arena and a focused strategy on combination medicines, Incannex Healthcare (IXHL) is poised to lead in innovative therapeutics targeting chronic conditions. The company aims to continue its advancement of IHL-42X and other promising candidates within its clinical pipeline.
For more information on Incannex Healthcare and its initiatives, visit www.incannex.com.