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Mdxhealth and University of Oxford to validate GPS test in largest randomized trial of treatment effectiveness in patients with localized prostate cancer

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Mdxhealth and University of Oxford to validate GPS test in largest randomized trial of treatment eff...

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AI Summary

Mdxhealth is partnering with the University of Oxford to validate its Genomic Prostate Score (GPS) through the UK's ProtecT trial. This landmark study aims to establish GPS as the first genomic classifier supported by randomized evidence, significantly impacting treatment decisions in localized prostate cancer and influencing clinical practice guidelines globally.

Trading Thesis

MDXH is well-positioned for growth as GPS validation may drive increased adoption among healthcare providers.

Market-Moving

  • A successful validation of GPS could lead to increased market share for MDXH.
  • Positive outcomes from the ProtecT trial may attract attention from investors.
  • Increased coverage and reimbursement could follow GPS's validation, enhancing revenue potential.
  • Collaboration with a prestigious institution like Oxford strengthens MDXH's market credibility.
  • MDXH's position in precision diagnostics may improve significantly post-trial results.

Key Facts

  • GPS testing is part of the UK ProtecT trial for localized prostate cancer.
  • The ProtecT trial is the largest randomized clinical trial focusing on localized prostate cancer.
  • MDXH has been working with University of Oxford since September 2023.
  • GPS is designed to predict prostate cancer progression and treatment outcomes.
  • The study leverages a comprehensive database of long-term clinical outcomes.

Companies Mentioned

  • University of Oxford (N/A): Collaboration increases credibility and may enhance GPS test adoption.

Corporate Developments

The collaboration focuses on corporate developments in precision diagnostics, indicating a shift toward integrating genomic insights in clinical practices. This could result in significant market disruption if successful, improving MDXH's standing and operational outcomes in a competitive industry.

FAQ

Why Bullish?

Validation of GPS by a reputable trial can lead to increased product adoption. Historical examples show that successful trials have positive impacts on similar companies' stock prices.

How important is it?

The article highlights significant advancements toward validating GPS, which could greatly influence both clinical practices and MDXH’s financial prospects, thus showcasing high relevance and importance for stakeholders.

Why Long Term?

The outcome of the ProtecT trial will take time to influence behaviors and adoption, but successful validation could lead to sustained market demand and financial performance.

Related Companies

ONCTEXDX

Mdxhealth Collaborates with University of Oxford to Validate GPS Test in Major Clinical Trial

IRVINE, CA – January XX, 2026 (GlobeNewswire) – Mdxhealth SA (NASDAQ: MDXH), a prominent player in precision diagnostics, has announced a significant advancement in its partnership with the University of Oxford. The initiation of the Genomic Prostate Score (GPS) testing is set to take place within the context of the UK ProtecT trial (Prostate Testing for Cancer and Treatment), marking a pivotal moment in prostate cancer treatment assessment. This landmark study aims to validate GPS as the first genomic classifier backed by randomized clinical trial evidence in an Active Surveillance cohort, further establishing its clinical relevance in predicting prostate cancer progression and long-term outcomes.

Significance of the ProtecT Trial

The UK ProtecT trial is recognized as the world’s largest randomized clinical trial assessing treatment effectiveness for localized prostate cancer. With over 1,500 men participating and tracked for more than two decades, this study provides unparalleled long-term data on clinical outcomes for Active Surveillance/Active Monitoring, Radical Prostatectomy (RP), and Radiotherapy (RT).

Michael K. McGarrity, Chief Executive Officer of Mdxhealth, emphasized, “This is a transformative moment for prostate cancer precision diagnostics. No other patient cohort offers this level of rigor, long-term follow-up, and potential impact on clinical practice guidelines, payer coverage, and provider adoption for patients diagnosed with localized prostate cancer.”

Enhancing Prostate Cancer Management

Professor Hamdy from the University of Oxford stated, “The ProtecT trial has been instrumental in shaping international standards for prostate cancer management. By integrating the Genomic Prostate Score (GPS) test, we are enhancing previous outcomes data with genomic insights that could revolutionize how healthcare providers assess risk and tailor treatment for patients globally.”

Building on Existing Research

This pivotal research builds on a partnership that began in September 2023, where Mdxhealth and the University of Oxford explored the link between GPS and prostate cancer progression through the ProMPT cohort. With the successful completion of ProMPT validation, the GPS-ProtecT study will now utilize one of the most extensive long-term datasets in prostate cancer research to illustrate the predictive capabilities of GPS in a robust prospective, randomized setting.

About Mdxhealth

Mdxhealth is a leading precison diagnostics company specializing in delivering actionable molecular information to tailor patient diagnosis and treatment. The company’s diagnostic tests employ proprietary genomic, epigenetic (methylation), exosomal, and other innovative molecular technologies, aiding physicians in diagnosing and prognosticating prostate cancer and other urologic diseases. Mdxhealth's U.S. headquarters and laboratory are located in Irvine, California, with additional facilities in Waltham, Massachusetts, and Plano, Texas, and its European headquarters situated in Herstal, Belgium.

For further information, visit mdxhealth.com, and follow the company on social media: Twitter, Facebook, and LinkedIn.

Forward-Looking Statements

This article contains forward-looking statements regarding Mdxhealth’s anticipated future performance and conditions within the market. These statements involve risks and uncertainties. Mdxhealth makes no commitment to update any forward-looking statements unless required by law or regulation. Furthermore, this article does not serve as an offer or invitation for the sale of any securities or assets of Mdxhealth, and no securities may be offered or sold without proper registration under applicable laws.

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