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The substantial drop in ZBIO's stock following trial results indicates a lack of investor confidence, particularly in light of competitive threats from Amgen’s Uplizna, which shows superior efficacy.
What happened, with direct paths to the underlying reporting
ZBIO stock dropped after Phase 3 INDIGO trial results for obexelimab. Obexelimab showed 56% reduction in IgG4-RD flare risk. Full clinical trial results are yet to be presented. Market competition from Amgen's Uplizna could pressure ZBIO. ZBIO plans FDA and EMA submissions in late 2026.
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