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Apellis Valuation Ignores Empaveli Potential, Says Analyst

Jan 21, 2026, 1:36 PM EST1 sourcesAI-analyzed

Why it may matterVerify against the original reporting

With BofA's upgrade reinforcing the positive trajectory of Empaveli's sales, similar past instances, where companies with underappreciated drug potential saw substantial stock price increases, lend credence to expected upward movement in APLS shares.

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Apellis Pharmaceuticals is experiencing significant growth with its rare kidney disease drug, Empaveli, prompting an upgrade from Bank of America that highlights an underappreciated opportunity in C3G. The positive early uptake, along with projected peak sales, suggests meaningful revenue potential in the coming years.

Apellis gains traction in rare kidney disease market with Empaveli.
Bank of America upgraded APLS, highlighting C3G opportunity.
Empaveli generated $27 million U.S. net revenue in Q3 2025.
BofA predicts $508 million in peak U.S. sales by 2033.
Syfovre's prefilled syringe could rejuvenate its market position.

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