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Aardvark Therapeutics Pauses Key Clinical Trial for ARD-101

Feb 27, 2026, 4:09 PM EST2 sourcesAI-analyzed

Why it may matterVerify against the original reporting

Historical instances, such as similar halts in trials, often lead to immediate negative reactions from investors. The uncertainty surrounding trial outcomes can diminish stock prices early and create volatility.

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What happened, with direct paths to the underlying reporting

Aardvark Therapeutics voluntarily pauses the Phase 3 HERO trial for ARD-101 due to cardiac safety concerns, delaying topline results expected in Q3 2026. The company is conducting a comprehensive data review and will provide further guidance by Q2 2026, maintaining collaboration with regulatory authorities and experts.

AARD pauses Phase 3 HERO trial due to cardiac safety concerns.
Voluntary halt affects ongoing enrollment and dosing of ARD-101.
No topline data expected in Q3 2026 as previously anticipated.
Comprehensive safety review will guide next steps for ARD-101.
Company maintains close collaboration with FDA and clinical experts.

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