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The positive signal in adolescents could drive near-term upside despite a negative primary endpoint; momentum in MPLT stock supports a near-term rally if data are interpreted as validating a targeted development path.
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MapLight Therapeutics' ML-004 missed its primary endpoint in the broad autism population, but demonstrated clinically meaningful irritability improvements in adolescents aged 12-17. The teen-focused signal could steer future trial strategy and sustain upside potential, even as regulatory readouts remain a key near-term risk.
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