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Initiation with an Overweight rating and >160% upside creates immediate price momentum, evidenced by a 22.9% intraday rise and a new 52-week high; catalyst risk is tied to August 2026 Phase 2 topline results and potential uptake advantages from dosing convenience.
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Cantor Fitzgerald initiated coverage of Silence with an Overweight rating, arguing divesiran could become a PV market challenger. August 2026 Phase 2 topline data and a dosing schedule every 6 or 12 weeks may unlock substantial valuation upside, supported by Phase 1 PV results and a $300 million market cap.
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