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SciSparc advances SCI-110 Phase IIb Tourette trial at Hannover Medical School

Jul 15, 2026, 8:43 AM EDT1 sourcesAI-analyzed
Why it may matterVerify against the original reporting

Phase IIb initiation and multi-site expansion represent a tangible development catalyst; positive data could improve regulatory prospects and drive upside, though outcome risk remains high given early-stage nature.

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SciSparc’s NeuroThera Labs initiated a Phase IIb site at Hannover Medical School for SCI-110 in adults with Tourette Syndrome, with Yale and Tel Aviv centers following. Building on Phase IIa’s 21% tic reduction, the randomized, double-blind, placebo-controlled cross-over study aims to further assess efficacy and safety, potentially informing a regulatory pathway if results are favorable.

  • SciSparc’s NeuroThera starts Phase IIb site at Hannover for SCI-110.
  • Phase IIb expands to Yale and Tel Aviv centers; randomized, double-blind, cross-over.
  • Phase IIa showed 21% tic reduction; primary endpoints at weeks 12 and 26.
  • SCI-110 combines dronabinol with palmitoylethanolamide in a single dose.
  • Tourette Syndrome is an unmet need; data could support future approvals.

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