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AKTXBullishCorporate Developmentsnews

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Akari and Whitehawk launch preclinical collaboration to test PH1 dual-payload ADCs

Jul 21, 2026, 7:08 AM EDT2 sourcesAI-analyzed

Why it may matterVerify against the original reporting

The collaboration introduces optionality and potential data-driven validation for AKTX’s dual-payload strategy, which could support upside if interim data are favorable and if the partnership leads to broader development opportunities.

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Akari Therapeutics and Whitehawk Therapeutics announced a strategic preclinical collaboration to evaluate combining Akari's PH1 spliceosome-modulating payload with Whitehawk’s TOP1i-ADC platform. The program aims to generate data on dual-payload compatibility and potential synergies, guiding future development decisions. Interim updates are expected as studies progress, with AKTX-101's IND-enabling work targeting mid-2027.

Akari and Whitehawk announce preclinical collaboration. Focus on PH1 with TOP1i ADC.
Multiple workstreams to assess dual payload compatibility. Interim data updates as studies progress.
IND-enabling study target mid-2027 for AKTX-101.
AKTX-102 targets CEACAM5; collaboration aims broader development.

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Akari and Whitehawk launch preclinical collaboration to test PH1 dual-payload ADCs

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