TLSA climbs on third patient PET data for intranasal foralumab in MSA
Jul 31, 2026, 1:52 PM EDT1 sourcesAI-analyzed
Why it may matterVerify against the original reporting
Positive imaging data in a niche neurodegenerative program can attract speculative interest; near-term MS topline data adds a second catalyst. However, small sample size and early-stage nature limit durability.
AI summary
What happened, with direct paths to the underlying reporting
Tiziana Life Sciences disclosed positive PET imaging results from the third patient in its Phase 2 MSA trial of intranasal foralumab, with significant neuroinflammation reductions (up to 34% SUV and 26% SUVR). Results echo the first two patients, bolstering the treatment’s inflammatory-modulation potential. The next catalyst is MS topline data due by late Q3/early Q4 2026, while the stock reacted modestly higher.
Third MSA patient shows 34% SUV decline and 26% SUVR drop after dosing.
Earlier two patients had ~35% SUV and ~24% SUVR reductions, aligning outcomes.
MSA topline data not provided; Phase 2a MS topline due late Q3/early Q4 2026.
TLSA shares rose about 6% on the news.
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