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SPRCBullishCorporate Developmentsnews
Medium materiality6/10

SciSparc advances SCI-110 Phase IIb with Yale US site expansion

Aug 5, 2026, 8:25 AM EDT1 sourcesAI-analyzed
Why it may matterVerify against the original reporting

Progress on a Phase IIb trial at a major US site (Yale) plus international sites improves pipeline visibility and potential future regulatory milestones; although data readouts are not yet disclosed, the expansion reduces execution risk and can support a re-rating if results are favorable.

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SciSparc said NeuroThera has launched the Phase IIb portion of SCI-110 at Yale, expanding trials to Hannover and Tel Aviv. Phase IIa demonstrated a 21% average tic reduction on the Yale Global Tic Severity Scale, underpinning the Phase IIb design. Positive data or faster enrollment could lift SPRC's CNS pipeline valuation in coming quarters.

  • Yale launches SCI-110 Phase IIb site; US center added.
  • Phase IIb also at Hannover and Tel Aviv sites.
  • Phase IIa showed 21% tic reduction on Yale Tic Severity Scale.
  • Primary endpoint: tic severity changes at weeks 12 and 26.
  • SCI-110 combines dronabinol with palmitoylethanolamide for Tourette syndrome.

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