SciSparc advances SCI-110 Phase IIb with Yale US site expansion
Aug 5, 2026, 8:25 AM EDT1 sourcesAI-analyzed
Why it may matterVerify against the original reporting
Progress on a Phase IIb trial at a major US site (Yale) plus international sites improves pipeline visibility and potential future regulatory milestones; although data readouts are not yet disclosed, the expansion reduces execution risk and can support a re-rating if results are favorable.
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What happened, with direct paths to the underlying reporting
SciSparc said NeuroThera has launched the Phase IIb portion of SCI-110 at Yale, expanding trials to Hannover and Tel Aviv. Phase IIa demonstrated a 21% average tic reduction on the Yale Global Tic Severity Scale, underpinning the Phase IIb design. Positive data or faster enrollment could lift SPRC's CNS pipeline valuation in coming quarters.
Yale launches SCI-110 Phase IIb site; US center added.
Primary endpoint: tic severity changes at weeks 12 and 26.
SCI-110 combines dronabinol with palmitoylethanolamide for Tourette syndrome.
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