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Corvus Initiates Phase 1b HS Trial for Soquelitinib, Expanding Pipeline

Sep 30, 2026, 5:16 PM EDT1 sourcesAI-analyzed

Why it may matterVerify against the original reporting

Direct trial enrollment news and expansion to a new indication can lift sentiment and valuation of a clinical-stage biotech, particularly if safety signals look favorable; typical SPAC-like volatility is possible until readouts.

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Corvus Pharmaceuticals announced the start of a Phase 1b hidradenitis suppurativa trial for soquelitinib, broadening its ITK-inhibition program. The study enlists up to 25 adults, dosed at 200 mg twice daily for 12 weeks with safety and HiSCR responses as primary endpoints. This milestone could enhance value via multi-indication potential alongside PTCL, AD, and ALPS programs.

Enrollment begun in Phase 1b HS trial for soquelitinib.
Up to 25 adults; 200 mg twice daily for 12 weeks.
Primary endpoint safety; HiSCR 50/75 at week 12.
Soquelitinib is in Phase 3 PTCL and Phase 2 AD; HS adds fourth indication.
Corvus targets ITK inhibition for autoimmune diseases and cancer.

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