EVX-01 phase 2 melanoma data shows 75% ORR with durable responses
Oct 2, 2026, 9:25 AM EDT1 sourcesAI-analyzed
Why it may matterVerify against the original reporting
Strong early signals (ORR 75%, durable responses) paired with major conference catalysts (SITC, ESMO) can attract buyers ahead of presentations; historical biotech data read-through often drives volatility near data events, with upside if durability persists.
AI summary
What happened, with direct paths to the underlying reporting
Evaxion reports new EVX-01 immune data from a phase 2 melanoma trial with pembrolizumab, showing systemic immune modulation beyond vaccine responses. Two-year data show ORR 75% (12/16) with four complete responses; 92% remain in response and no relapses. SITC 2026 and ESMO 2026 presentations could drive upside if durability and standalone efficacy persist.
Phase 2 melanoma data: ORR 75% (12/16) with 4 CRs.
2-year durability: 92% still responding; no relapses observed.
86% of EVX-01 neoantigen targets triggered tumor-specific responses.
Three-year data to be presented at ESMO 2026 on Oct 24.
SITC 2026 will feature EVX-01 oral and poster data with pembrolizumab.
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