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Regeneron Reports Positive 84-Week Pasatru Data in FOP Trial

Oct 12, 2026, 1:59 PM EDT1 sourcesAI-analyzed
Why it may matterVerify against the original reporting

Durable 84-week efficacy improves confidence in Pasatru's clinical value; could drive sentiment and valuation, especially if regulatory and payer pathways remain favorable, though market size is small.

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What happened, with direct paths to the underlying reporting

Regeneron announced positive 84-week results from the Phase 3 OPTIMA trial of Pasatru in adults with fibrodysplasia ossificans progressiva (FOP). Data presented at ASBMR show sustained efficacy with reduced HO lesions and flare-ups, plus a consistent safety profile through week 84, supporting long-term disease control and potential for future labeling considerations.

  • Pasatru shows 84-week efficacy in FOP OPTIMA trial.
  • 56-week data showed reductions in new HO lesions and flare-ups.
  • ASBMR late-breaking data support long-term disease control and safety.
  • Regeneron announces sustained Pasatru results, potential for label/payer considerations.

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