Zealand Pharma announced additional Phase 2 ZUPREME-1 data on petrelintide at ADA 2026, showing up to 10.7% weight loss at Week 42 versus placebo with tolerability similar to placebo. Phase 3 trials are planned to begin in H2 2026, and Roche has endorsed co-development and co-commercialization, potentially unlocking significant upside for ZEAL’s obesity/metabolic health program.
Roche partners with Zealand Pharma for a $5.3 billion weight-loss drug deal. Petrelintide, a weekly injection, targets better tolerability compared to existing drugs. Zealand Pharma shares surged 29% in response to the deal announcement. Analysts view Roche as a beneficial partner for Zealand Pharma's ambitions. Potential drug launch timeframe estimated around 2029.