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22nd Century Announces First Shipments of Pinnacle VLN® Products to Top 5 C-Store Chain Locations Across 12 States

1. 22nd Century launches Pinnacle VLN® Gold and Menthol cigarettes. 2. New products are scheduled to launch at 1,000 locations on September 1, 2025. 3. VLN® products comply with the FDA's proposed low nicotine standards. 4. 22nd Century aims to expand its VLN® product offerings and market reach. 5. The launch reinforces public health initiatives by offering reduced nicotine options.

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Why Bullish?

The successful product launch indicates strong demand and market potential for reduced nicotine cigarettes, potentially increasing XXII's revenues. Historical examples include increased sales following FDA approval of similar health-conscious products.

How important is it?

This announcement underscores XXII's innovative advancements in the tobacco industry which may attract investors and increase stock value due to the expansion of a unique and compliant product range.

Why Short Term?

The upcoming product launch date of September 2025 indicates immediate market activity, placing focus on short-term revenue generation and investor interest. Initial sales often reflect immediate reaction in stock prices post-launch.

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Pinnacle VLN® from 22nd Century Gains 2nd Early Adopter to Join Popular Pinnacle Branded Conventional Cigarette Products Already Sold at Top-5 U.S. C-Store Chain MOCKSVILLE, N.C., Aug. 04, 2025 (GLOBE NEWSWIRE) -- 22nd Century Group, Inc. (Nasdaq: XXII), the only tobacco products company that has for 27 years led and continues to lead the fight against the harms of smoking driven by nicotine addiction, today announced the first shipments of its new Pinnacle VLN® Gold and Pinnacle VLN® Menthol reduced nicotine content cigarettes into distribution. These initial Pinnacle VLN® shipments will support a sales launch expected on September 1, 2025 at almost 1,000 locations across 12 states for a top-5 U.S. convenience store chain. “Pinnacle’s conventional cigarette product lines have been very successful for this c-store chain, establishing strong brand loyalty with customers. We are excited to launch our new Pinnacle VLN® products, representing our second early adopter partner VLN® brand, expanding the reach and awareness of this innovative solution designed specifically to give smokers a choice with respect to their nicotine intake with an eye on improving public health,” said Larry Firestone, Chief Executive Officer of 22nd Century Group. “This opportunity reinforces the validity of the FDA’s recent proposed low nicotine mandate that would require all combustible tobacco products to be less than 0.7 mg/g. A standard that VLN® products deliver on. This equates to roughly a 95% reduction in nicotine compared to traditional cigarettes.” Additional Pinnacle VLN® states and locations for this c-store chain will continue to be added, plus re-order inventory with the c-store chain’s distributor. Pinnacle VLN® cigarettes expand the total Pinnacle branded product offerings which include conventional cigarettes, cigarillos and moist snuff, which are all supplied by 22nd Century. VLN® products using proprietary tobacco grown with 95% reduced nicotine content are the first and only combusted tobacco products to comply with the FDA’s proposed new Tobacco Product Standard for Nicotine Yield of Cigarettes and Certain Other Combusted Tobacco Products. “VLN® products from 22nd Century are the first and only combusted cigarette authorized by the U.S. Food and Drug Administration specifically to reduce nicotine intake and therefore affect the smoking habit, backed by extensive clinical research that shows a 95% reduced nicotine cigarette can be an effective way to reduce total smoking,” said Firestone. “Our goal is to expand VLN® products into as many brands as possible to widen the reach of this important harm reduction product enabling 22nd Century to stay in the forefront of the Tobacco Harm Reduction Movement.” About 22nd Century Group, Inc. 22nd Century Group is pioneering the nicotine harm reduction movement in the tobacco industry enabling smokers to take control of their nicotine consumption through combustible cigarettes. We created our flagship product, the VLN® cigarette, to give traditional cigarette smokers an authentic and familiar alternative in the form of a combustible cigarette that helps them take control of their nicotine consumption. VLN® cigarettes have 95% less nicotine than the traditional cigarette and have been proven to allow consumers to greatly reduce their nicotine consumption. Instead of offering new ways of delivering nicotine to addicted smokers, we offer smokers in the form that they are used to, the option to take control of their nicotine consumption and make informed and more productive choices, including the choice to avoid addictive levels of nicotine altogether. Our proprietary non-GMO reduced nicotine tobacco blends are made possible by comprehensive and patented technologies and tobacco plants that regulate nicotine biosynthesis activities in the tobacco plant, resulting in full flavor and high yield with 95% less nicotine. Our extensive patent portfolio has been developed to ensure we have the only low nicotine combustible cigarette in the United States and critical international markets. VLN® is a registered trademark of 22nd Century Limited LLC. Learn more at xxiicentury.com, on X (formerly Twitter), on LinkedIn, and on YouTube. Learn more about VLN® at tryvln.com. Cautionary Note Regarding Forward-Looking Statements Except for historical information, all of the statements, expectations, and assumptions contained in this press release are forward-looking statements, including but not limited to our full year business outlook. Forward-looking statements typically contain terms such as “anticipate,” “believe,” “consider,” “continue,” “could,” “estimate,” “expect,” “explore,” “foresee,” “goal,” “guidance,” “intend,” “likely,” “may,” “plan,” “potential,” “predict,” “preliminary,” “probable,” “project,” “promising,” “seek,” “should,” “will,” “would,” and similar expressions. Forward-looking statements include, but are not limited to, statements regarding (i) our cost reduction initiatives, (ii) our expectations regarding regulatory enforcement, including our ability to receive an exemption from new regulations, (iii) our financial and operating performance and (iv) our expectations for our business interruption insurance claim. Actual results might differ materially from those explicit or implicit in forward-looking statements. Important factors that could cause actual results to differ materially are set forth in “Risk Factors” in the Company’s Annual Report on Form 10-K filed on March 20, 2025 and Quarterly Report on Form 10-Q filed on May 13, 2025. All information provided in this release is as of the date hereof, and the Company assumes no obligation to and does not intend to update these forward-looking statements, except as required by law. Investor Relations & Media ContactMatt KrepsInvestor Relations22nd Century Groupmkreps@xxiicentury.com214-597-8200

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