
Alto Neuroscience, Inc. (NYSE:ANRO), a clinical-stage biopharmaceutical company focused on the development of novel precision medicines for neuropsychiatric disorders, today congratulates founder and CEO Amit Etkin,

<p xmlns="http://www.w3.org/1999/xhtml">
Alto Neuroscience, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/quote/ANRO">ANRO</a>), a clinical-stage biopharmaceutical company focused on the development of novel precision medicines for neuropsychiatric disorders, today congratulates founder and CEO Amit Etkin, M.D., Ph.D. on receiving the Transformational Research Award from the VP&amp;S Alumni Association at Columbia University Vagelos College of Physicians and Surgeons. This award honors VP&amp;S alumni who are making transformational contributions to biomedical research within 25 years of graduation.

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"Having led global neuroscience R&amp;D efforts for many years, I recognize that true transformation requires moving beyond the &#39;one-size-fits-all&#39; model," said Husseini Manji, M.D., member of the Alto Neuroscience Board of Directors and former Global Head of Neuroscience at Johnson &amp; Johnson. "Amit's work, honored today by Columbia, represents the successful bridging of elite academic inquiry and industrial-scale innovation. He has moved the needle from theoretical biomarkers to a clinical-stage pipeline that has the potential to redefine how we treat mental health in a markedly improved manner."

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Dr. Etkin earned his MD and PhD with distinction from Columbia University under Nobel laureate Dr. Eric Kandel, joined the Stanford faculty in 2010, and received the NIH Director's Pioneer Award — the most competitive NIH grant and the first ever awarded in clinical psychiatry. He founded Alto in 2019, where he leads development of the Precision Psychiatry Platform&#x2122;, which uses brain-based biomarkers to identify patients most likely to respond to specific treatments. Alto's clinical-stage pipeline programs span major depressive disorder, bipolar depression, treatment-resistant depression, and schizophrenia, with multiple mid- to late-stage data readouts expected across the coming two years.

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"I am deeply honored to receive this award from Columbia," said Dr. Etkin. "My years at Columbia — learning from some of the most brilliant scientific minds in the world, including Dr. Kandel — shaped my conviction that understanding the brain at a fundamental level is the key to transforming how we treat psychiatric disease. That conviction truly motivates our work at Alto, and I dedicate this recognition to the patients we serve and the remarkable team at Alto working to bring better treatments to them."

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For more information about the award, visit <a xmlns="http://www.w3.org/1999/xhtml" rel="nofollow" href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.vagelos.columbia.edu%2Fnews%2Famit-etkin-06-winner-transformational-research-award&amp;esheet=54536571&amp;newsitemid=20260515727151&amp;lan=en-US&amp;anchor=https%3A%2F%2Fwww.vagelos.columbia.edu%2Fnews%2Famit-etkin-06-winner-transformational-research-award&amp;index=1&amp;md5=102a5991044b74bbf2a3ab273dcd2105" shape="rect">https://www.vagelos.columbia.edu/news/amit-etkin-06-winner-transformational-research-award</a>.

</p><p xmlns="http://www.w3.org/1999/xhtml">
<b xmlns="http://www.w3.org/1999/xhtml">About Alto Neuroscience</b>

</p><p xmlns="http://www.w3.org/1999/xhtml">
Alto Neuroscience is a clinical-stage biopharmaceutical company with a mission to redefine psychiatry by leveraging neurobiology to develop personalized and highly effective treatment options. Alto's Precision Psychiatry Platform&#x2122; measures brain biomarkers by analyzing EEG activity, neurocognitive assessments, wearable data, and other factors to better identify which patients are more likely to respond to Alto product candidates. Alto's clinical-stage pipeline includes novel drug candidates in bipolar depression, major depressive disorder, treatment resistant depression, schizophrenia, and other mental health conditions. For more information, visit <a xmlns="http://www.w3.org/1999/xhtml" rel="nofollow" href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.altoneuroscience.com%2F&amp;esheet=54536571&amp;newsitemid=20260515727151&amp;lan=en-US&amp;anchor=www.altoneuroscience.com&amp;index=2&amp;md5=800e996cf81e39bc8838dc15598434e8" shape="rect">www.altoneuroscience.com</a> or <a xmlns="http://www.w3.org/1999/xhtml" rel="nofollow" href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fx.com%2FAltoNeuro&amp;esheet=54536571&amp;newsitemid=20260515727151&amp;lan=en-US&amp;anchor=follow+Alto+on+X&amp;index=3&amp;md5=e7c18147f05fe6f61838d7b3fbca3f23" shape="rect">follow Alto on X</a>.

</p><p xmlns="http://www.w3.org/1999/xhtml">
<b xmlns="http://www.w3.org/1999/xhtml">Forward-Looking Statements</b>

</p><p xmlns="http://www.w3.org/1999/xhtml">
This press release may contain forward-looking statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These statements may be identified by words such as "anticipates," "expects," "may," "will," and variations of these words or similar expressions that are intended to identify forward-looking statements, although not all forward-looking statements contain these words. Forward-looking statements in this press release include, but are not limited to, statements regarding Alto's expectations about the potential benefits, activity, effectiveness, tolerability and safety of its product candidates and Precision Psychiatry Platform ("Platform"); Alto's expectations with regard to its research and development programs and clinical trials, including the timing and availability of data from such trials; and other statements that are not historical fact. Actual results or events could differ materially from the plans, intentions and expectations disclosed in these forward-looking statements as a result of various factors, including the availability and timing of results from clinical trials; and other important factors, any of which could cause Alto's actual results to differ from those contained in the forward-looking statements, which are described in greater detail in the section titled "Risk Factors" in Alto's Annual Report on Form 10-K for the fiscal year ended December 31, 2025 filed with the Securities and Exchange Commission ("SEC") as well as in other filings Alto may make with the SEC in the future. Any forward-looking statements contained in this press release speak only as of the date hereof, and Alto expressly disclaims any obligation to update any forward-looking statements contained herein, whether because of any new information, future events, changed circumstances or otherwise, except as required by law.

</p><p xmlns="http://www.w3.org/1999/xhtml">
<b xmlns="http://www.w3.org/1999/xhtml">Availability of Information on Alto's Website</b>

</p><p xmlns="http://www.w3.org/1999/xhtml">
Alto routinely uses its investor relations <a xmlns="http://www.w3.org/1999/xhtml" rel="nofollow" href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Finvestors.altoneuroscience.com%2Foverview%2Fdefault.aspx&amp;esheet=54536571&amp;newsitemid=20260515727151&amp;lan=en-US&amp;anchor=website&amp;index=4&amp;md5=377452f2e818675b6c31cac6a3f6a086" shape="rect">website</a> to post presentations to investors and other important information, including information that may be material. Accordingly, Alto encourages investors and others interested in Alto to review the information it makes public on its investor relations website.

</p><p xmlns="http://www.w3.org/1999/xhtml"><img xmlns="http://www.w3.org/1999/xhtml" alt="" src="https://cts.businesswire.com/ct/CT?id=bwnews&amp;sty=20260515727151r1&amp;sid=benz2&amp;distro=nx&amp;lang=en" style="width:0;height:0"></img><span xmlns="http://www.w3.org/1999/xhtml" class="bwct31415"></span></p><p xmlns="http://www.w3.org/1999/xhtml" id="mmgallerylink"><span xmlns="http://www.w3.org/1999/xhtml" id="mmgallerylink-phrase">View source version on businesswire.com: </span><span xmlns="http://www.w3.org/1999/xhtml" id="mmgallerylink-link"><a xmlns="http://www.w3.org/1999/xhtml" href="https://www.businesswire.com/news/home/20260515727151/en/" rel="nofollow">https://www.businesswire.com/news/home/20260515727151/en/</a></span></p><p xmlns="http://www.w3.org/1999/xhtml">
<b xmlns="http://www.w3.org/1999/xhtml">Investor and Media Contact: 
</b><br xmlns="http://www.w3.org/1999/xhtml"></br>Nick Smith
<br xmlns="http://www.w3.org/1999/xhtml"></br><a xmlns="http://www.w3.org/1999/xhtml" rel="nofollow" href="mailto:investors@altoneuroscience.com" shape="rect">investors@altoneuroscience.com 
</a><br xmlns="http://www.w3.org/1999/xhtml"></br><a xmlns="http://www.w3.org/1999/xhtml" rel="nofollow" href="mailto:media@altoneuroscience.com" shape="rect">media@altoneuroscience.com</a>

</p>

ANRO

Alto Neuroscience CEO Amit Etkin, M.D., Ph.D. Receives Columbia University Transformational Research Award

CEO Amit Etkin ReceivesPrestigious Award, Boosting ANRO's Credibility

<section class="insight" data-version="1">
  <section data-block="information">
    <h3>Information</h3>
    <p>Alto Neuroscience, Inc. (NYSE:ANRO), a clinical-stage biopharmaceutical company focused on the development of novel precision medicines for neuropsychiatric disorders, today congratulates founder and CEO Amit Etkin,</p>
  </section>

  <section data-block="ai-summary-paragraph">
    <h3>AI Summary</h3>
    <p>Alto Neuroscience&#039;s CEO, Dr. Amit Etkin, received a Transformational Research Award, enhancing the company’s credibility in psychiatric treatment innovation. The recognition potentially increases investor confidence as multiple clinical trials are expected to report data within the next two years.</p>
  </section>

  <section data-block="ai-summary-bullets">
    <h3>Key Points</h3>
    <ul><li>Alto Neuroscience congratulates CEO Amit Etkin for his award.</li><li>Etkin’s work bridges academic research and industry innovation.</li><li>Alto&#039;s pipeline targets major psychiatric disorders.</li><li>Mid- to late-stage data readouts expected within two years.</li><li>Award highlights Alto&#039;s mission to transform psychiatric treatment.</li></ul>
  </section>

  <section data-block="companies-mentioned">
    <h3>Companies Mentioned</h3>
    <ul><li><strong>Johnson &amp; Johnson (JNJ)</strong>: Their former neuroscience head endorses Etkin&#039;s contributions.</li><li><strong>Columbia University (N/A)</strong>: Recognition from a prestigious institution adds credibility.</li></ul>
  </section>

  <section data-block="category">
    <h3>Corporate Developments</h3>
    <p>The recognition of Dr. Etkin aligns with industry news on innovation in neuropsychiatry, underlining various advances in treatment personalization that could drive market interest.</p>
  </section>

  <section data-block="market-moving">
    <h3>Market-Moving</h3>
    <ul><li>Positive recognition may improve investor sentiment and stock price.</li><li>Successful trial data in upcoming years could validate Alto’s approach.</li><li>Increased attention on innovative treatments may attract partnerships or funding.</li><li>Potential growth in mental health sector could expand Alto’s market share.</li></ul>
  </section>

  <section data-block="key-facts">
    <h3>Key Facts</h3>
    <ul><li>Amit Etkin recognized for his contributions within 25 years of graduation.</li><li>Alto&#039;s pipeline includes treatments for major depressive disorder, bipolar depression, and schizophrenia.</li><li>Multiple mid- to late-stage clinical trial results expected in two years.</li><li>The Precision Psychiatry Platform™ uses brain-based biomarkers for targeted treatment.</li></ul>
  </section>

  <section data-block="trading-thesis">
    <h3>Trading Thesis</h3>
    <p>ANRO could see upward momentum as credibility increases with clinical trial advancements.</p>
  </section>
</section>


<p xmlns="http://www.w3.org/1999/xhtml">
Alto Neuroscience, Inc. (NYSE:<a class="ticker" href="https://www.benzinga.com/quote/ANRO">ANRO</a>), a clinical-stage biopharmaceutical company focused on the development of novel precision medicines for neuropsychiatric disorders, today congratulates founder and CEO Amit Etkin, M.D., Ph.D. on receiving the Transformational Research Award from the VP&amp;S Alumni Association at Columbia University Vagelos College of Physicians and Surgeons. This award honors VP&amp;S alumni who are making transformational contributions to biomedical research within 25 years of graduation.

</p><p xmlns="http://www.w3.org/1999/xhtml">
"Having led global neuroscience R&amp;D efforts for many years, I recognize that true transformation requires moving beyond the &#39;one-size-fits-all&#39; model," said Husseini Manji, M.D., member of the Alto Neuroscience Board of Directors and former Global Head of Neuroscience at Johnson &amp; Johnson. "Amit's work, honored today by Columbia, represents the successful bridging of elite academic inquiry and industrial-scale innovation. He has moved the needle from theoretical biomarkers to a clinical-stage pipeline that has the potential to redefine how we treat mental health in a markedly improved manner."

</p><p xmlns="http://www.w3.org/1999/xhtml">
Dr. Etkin earned his MD and PhD with distinction from Columbia University under Nobel laureate Dr. Eric Kandel, joined the Stanford faculty in 2010, and received the NIH Director's Pioneer Award — the most competitive NIH grant and the first ever awarded in clinical psychiatry. He founded Alto in 2019, where he leads development of the Precision Psychiatry Platform&#x2122;, which uses brain-based biomarkers to identify patients most likely to respond to specific treatments. Alto's clinical-stage pipeline programs span major depressive disorder, bipolar depression, treatment-resistant depression, and schizophrenia, with multiple mid- to late-stage data readouts expected across the coming two years.

</p><p xmlns="http://www.w3.org/1999/xhtml">
"I am deeply honored to receive this award from Columbia," said Dr. Etkin. "My years at Columbia — learning from some of the most brilliant scientific minds in the world, including Dr. Kandel — shaped my conviction that understanding the brain at a fundamental level is the key to transforming how we treat psychiatric disease. That conviction truly motivates our work at Alto, and I dedicate this recognition to the patients we serve and the remarkable team at Alto working to bring better treatments to them."

</p><p xmlns="http://www.w3.org/1999/xhtml">
For more information about the award, visit <a xmlns="http://www.w3.org/1999/xhtml" rel="nofollow" href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.vagelos.columbia.edu%2Fnews%2Famit-etkin-06-winner-transformational-research-award&amp;esheet=54536571&amp;newsitemid=20260515727151&amp;lan=en-US&amp;anchor=https%3A%2F%2Fwww.vagelos.columbia.edu%2Fnews%2Famit-etkin-06-winner-transformational-research-award&amp;index=1&amp;md5=102a5991044b74bbf2a3ab273dcd2105" shape="rect">https://www.vagelos.columbia.edu/news/amit-etkin-06-winner-transformational-research-award</a>.

</p><p xmlns="http://www.w3.org/1999/xhtml">
<b xmlns="http://www.w3.org/1999/xhtml">About Alto Neuroscience</b>

</p><p xmlns="http://www.w3.org/1999/xhtml">
Alto Neuroscience is a clinical-stage biopharmaceutical company with a mission to redefine psychiatry by leveraging neurobiology to develop personalized and highly effective treatment options. Alto's Precision Psychiatry Platform&#x2122; measures brain biomarkers by analyzing EEG activity, neurocognitive assessments, wearable data, and other factors to better identify which patients are more likely to respond to Alto product candidates. Alto's clinical-stage pipeline includes novel drug candidates in bipolar depression, major depressive disorder, treatment resistant depression, schizophrenia, and other mental health conditions. For more information, visit <a xmlns="http://www.w3.org/1999/xhtml" rel="nofollow" href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.altoneuroscience.com%2F&amp;esheet=54536571&amp;newsitemid=20260515727151&amp;lan=en-US&amp;anchor=www.altoneuroscience.com&amp;index=2&amp;md5=800e996cf81e39bc8838dc15598434e8" shape="rect">www.altoneuroscience.com</a> or <a xmlns="http://www.w3.org/1999/xhtml" rel="nofollow" href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Fx.com%2FAltoNeuro&amp;esheet=54536571&amp;newsitemid=20260515727151&amp;lan=en-US&amp;anchor=follow+Alto+on+X&amp;index=3&amp;md5=e7c18147f05fe6f61838d7b3fbca3f23" shape="rect">follow Alto on X</a>.

</p><p xmlns="http://www.w3.org/1999/xhtml">
<b xmlns="http://www.w3.org/1999/xhtml">Forward-Looking Statements</b>

</p><p xmlns="http://www.w3.org/1999/xhtml">
This press release may contain forward-looking statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These statements may be identified by words such as "anticipates," "expects," "may," "will," and variations of these words or similar expressions that are intended to identify forward-looking statements, although not all forward-looking statements contain these words. Forward-looking statements in this press release include, but are not limited to, statements regarding Alto's expectations about the potential benefits, activity, effectiveness, tolerability and safety of its product candidates and Precision Psychiatry Platform ("Platform"); Alto's expectations with regard to its research and development programs and clinical trials, including the timing and availability of data from such trials; and other statements that are not historical fact. Actual results or events could differ materially from the plans, intentions and expectations disclosed in these forward-looking statements as a result of various factors, including the availability and timing of results from clinical trials; and other important factors, any of which could cause Alto's actual results to differ from those contained in the forward-looking statements, which are described in greater detail in the section titled "Risk Factors" in Alto's Annual Report on Form 10-K for the fiscal year ended December 31, 2025 filed with the Securities and Exchange Commission ("SEC") as well as in other filings Alto may make with the SEC in the future. Any forward-looking statements contained in this press release speak only as of the date hereof, and Alto expressly disclaims any obligation to update any forward-looking statements contained herein, whether because of any new information, future events, changed circumstances or otherwise, except as required by law.

</p><p xmlns="http://www.w3.org/1999/xhtml">
<b xmlns="http://www.w3.org/1999/xhtml">Availability of Information on Alto's Website</b>

</p><p xmlns="http://www.w3.org/1999/xhtml">
Alto routinely uses its investor relations <a xmlns="http://www.w3.org/1999/xhtml" rel="nofollow" href="https://cts.businesswire.com/ct/CT?id=smartlink&amp;url=https%3A%2F%2Finvestors.altoneuroscience.com%2Foverview%2Fdefault.aspx&amp;esheet=54536571&amp;newsitemid=20260515727151&amp;lan=en-US&amp;anchor=website&amp;index=4&amp;md5=377452f2e818675b6c31cac6a3f6a086" shape="rect">website</a> to post presentations to investors and other important information, including information that may be material. Accordingly, Alto encourages investors and others interested in Alto to review the information it makes public on its investor relations website.

</p><p xmlns="http://www.w3.org/1999/xhtml"><img xmlns="http://www.w3.org/1999/xhtml" alt="" src="https://cts.businesswire.com/ct/CT?id=bwnews&amp;sty=20260515727151r1&amp;sid=benz2&amp;distro=nx&amp;lang=en" style="width:0;height:0"></img><span xmlns="http://www.w3.org/1999/xhtml" class="bwct31415"></span></p><p xmlns="http://www.w3.org/1999/xhtml" id="mmgallerylink"><span xmlns="http://www.w3.org/1999/xhtml" id="mmgallerylink-phrase">View source version on businesswire.com: </span><span xmlns="http://www.w3.org/1999/xhtml" id="mmgallerylink-link"><a xmlns="http://www.w3.org/1999/xhtml" href="https://www.businesswire.com/news/home/20260515727151/en/" rel="nofollow">https://www.businesswire.com/news/home/20260515727151/en/</a></span></p><p xmlns="http://www.w3.org/1999/xhtml">
<b xmlns="http://www.w3.org/1999/xhtml">Investor and Media Contact: 
</b><br xmlns="http://www.w3.org/1999/xhtml"></br>Nick Smith
<br xmlns="http://www.w3.org/1999/xhtml"></br><a xmlns="http://www.w3.org/1999/xhtml" rel="nofollow" href="mailto:investors@altoneuroscience.com" shape="rect">investors@altoneuroscience.com 
</a><br xmlns="http://www.w3.org/1999/xhtml"></br><a xmlns="http://www.w3.org/1999/xhtml" rel="nofollow" href="mailto:media@altoneuroscience.com" shape="rect">media@altoneuroscience.com</a>

</p>

Alto Neuroscience's CEO, Dr. Amit Etkin, received a Transformational Research Award, enhancing the company’s credibility in psychiatric treatment innovation. The recognition potentially increases investor confidence as multiple clinical trials are expected to report data within the next two years.

Alto Neuroscience CEO Amit Etkin, M.D., Ph.D. Receives Columbia University Transformational Research Award

AI Summary

Sentiment Rationale

Trading Thesis

Market-Moving

Key Facts

Companies Mentioned

Corporate Developments

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