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Applied DNA Positions TR8 PGx Testing Service as Pre-Emptive Testing for Safety of Fluoropyrimidine-Based Cancer Therapeutics Following Publication of Food and Drug Administration Safety Announcement

1. APDN's clinical lab targets specific pharmacogenomics with new testing subpanels. 2. The strategy focuses on tailored testing for cancer patients' drug metabolism.

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Why Bullish?

The shift towards personalized medicine and targeted treatments in pharmacogenomics typically indicates growth potential. Historical references show that companies adapting to patient-specific strategies often experience stock price appreciation.

How important is it?

The implementation of tailored subpanels indicates innovation and responsiveness to market needs, which is crucial for APDN's future profitability.

Why Long Term?

The strategic repositioning could lead to sustained revenue growth in future quarters, aligning with healthcare trends favoring personalized approaches.

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- Company Revamps Pharmacogenomics Go-To-Market Strategy, Targets Validated PGx Assay Towards Specific Use Cases - STONY BROOK, NY / ACCESS Newswire / April 1, 2025 / Applied DNA Sciences, Inc. (NASDAQ:APDN) (Applied DNA or the "Company"), a leader in PCR-based DNA technologies, today announced that Applied DNA Clinical Labs (ADCL), its wholly-owned clinical laboratory subsidiary, is repositioning its TR8™ PGx pharmacogenomics testing service to offer tailored subpanels for indication-specific use cases in addition to full panel testing. The first subpanel under ADCL's new go-to-market strategy is for the pre-emptive testing of patients with genetic variants of the DPYD gene that correlate to potentially reduced or absent DPD enzyme activity necessary to metabolize fluoropyrimidines, specifically capecitabine (branded Xeloda) and fluorouracil (5-FU), two chemotherapy drugs that are widely used as part of the standard of care treatment for patients with certain cancers.

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