SEATTLE, WA / ACCESS Newswire / August 12, 2026 / Aptevo Therapeutics Inc. (NASDAQ:APVO) (&#34;Aptevo&#34; or the &#34;Company&#34;), a clinical-stage biotechnology company developing novel multispecific immuno-oncology

<p><strong id="dateline">SEATTLE, WA / <a href='https://www.accessnewswire.com/'>ACCESS Newswire</a> / August 12, 2026 / </strong>Aptevo Therapeutics Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/quote/APVO">APVO</a>) ("Aptevo" or the "Company"), a clinical-stage biotechnology company developing novel multispecific immuno-oncology therapeutics, today announced it has entered into warrant inducement letter agreements with certain holders of its existing common warrants (the "Existing Warrants"), pursuant to which such holders have agreed to exercise in full for cash their Existing Warrants to purchase up to an aggregate of 254,922 shares of common stock of the Company ("common stock") at a reduced exercise price of $4.03 per share. In consideration for such cash exercises, the Company will issue new unregistered common stock purchase warrants (the "Inducement Warrants") to purchase up to an aggregate of 1,274,610 shares of common stock at an exercise price of $4.03 per share. The Inducement Warrants will be exercisable on or after the date on which the Company obtains the required stockholder approval and will expire five years after their initial exercise date. The shares of common stock issuable upon exercise of the Existing Warrants are registered pursuant to effective registration statements on Form S-1 (File No. 333-288061),Form S-1MEF (File No. 333-288134), Form S-3 (File No. 333-284969) and Form S-3 (File No. 333-283983).</p><p>Separately, pursuant to a securities purchase agreement, the Company agreed to sell to certain purchasers in a private placement (the "PIPE") up to 861,708 unregistered shares of common stock (the "Shares") at a purchase price of $4.03 per share (or, at a purchaser's election to comply with a 4.99% or 9.99% beneficial ownership limitation, pre-funded common stock purchase warrants (the "Pre-Funded Warrants") to purchase up to 861,708 shares in lieu of such shares), together with common stock purchase warrants (the "Common Warrants") to purchase up to 4,308,540 shares of common stock at an exercise price of $4.03 per share. The Pre-Funded Warrants will be exercisable immediately and will expire upon exercise in full, and the Common Warrants will be exercisable on or after the date on which the Company obtains the required stockholder approval and will expire five years after their initial exercise date (together, the "PIPE Warrants").</p><p>The aggregate gross proceeds from the transactions described herein are expected to total approximately $4.5 million, before deducting placement agent fees and expenses.</p><p>Roth Capital Partners, LLC is acting as the Company's exclusive placement agent in connection with these transactions.</p><p>The transactions are expected to close on or about August 13, 2026, subject to satisfaction of customary closing conditions. The Company intends to use the net proceeds from the transactions for working capital purposes.</p><p>The Inducement Warrants, the Shares, the Pre-Funded Warrants and the Common Warrants described above were offered in private placement transactions pursuant to Section 4(a)(2) of the Securities Act of 1933, as amended (the "1933 Act"), and Rule 506 promulgated thereunder, as applicable, and, along with the shares of common stock issuable upon exercise of the Inducement Warrants, the Pre-Funded Warrants and the Common Warrants, have not been registered under the 1933 Act and may not be offered or sold in the United States absent registration with the Securities and Exchange Commission ("SEC") or an applicable exemption from such registration requirements. The Company has agreed to file a registration statement with the SEC covering the resale of the Shares and the shares of common stock issuable upon exercise of the Inducement Warrants, the Pre-Funded Warrants and the Common Warrants.</p><p>This press release shall not constitute an offer to sell or a solicitation of an offer to buy nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or exemption under the securities laws of any such state or jurisdiction.</p><p><strong>About Aptevo Therapeutics</strong></p><p>Aptevo Therapeutics Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/quote/APVO">APVO</a>) is a clinical-stage biotechnology company developing novel multispecific immunotherapies for the treatment of cancer. The Company's lead clinical candidate, mipletamig, is currently being evaluated in frontline acute myeloid leukemia in combination with standard-of-care venetoclax + azacitidine. Aptevo's pipeline is generated from its proprietary ADAPTIR<sup>&#8482;</sup> and ADAPTIR-FLEX<sup>&#8482;</sup> platforms and includes bispecific and trispecific candidates designed to create multiple oncology value drivers across hematologic malignancies and solid tumors. In preclinical development, Aptevo is advancing APVO451, a nectin-4-targeted trispecific immunotherapy candidate for solid tumors and is pursuing strategic opportunities in radiopharmaceutical therapeutics to extend its tumor-targeting expertise into additional cancer treatment approaches. For more information, visit <a rel="nofollow" href="https://pr.report/f9pmaK8b"><strong>www.aptevotherapeutics.com</strong></a>.</p><p><strong>Cautionary Note Regarding Forward-Looking Statement</strong></p><p>This press release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements, other than statements of historical fact, including, without limitation, statements regarding the closing of the transactions described herein, the satisfaction of the closing conditions of the transactions, the use of net proceeds from the transactions, and any other statements containing the words "may," "continue to," "believes," "knows," "expects," "optimism," "potential," "designed," "promising," "plans," "will" and similar expressions are intended to identify forward-looking statements. These forward-looking statements are based on Aptevo's current intentions, beliefs, and expectations regarding future events. Aptevo cannot guarantee that any forward-looking statement will be accurate. Investors should realize that if underlying assumptions prove inaccurate or unknown risks or uncertainties materialize, actual results could differ materially from Aptevo's expectations. Investors are, therefore, cautioned not to place undue reliance on any forward-looking statement.</p><p>There are several important factors that could cause Aptevo's actual results to differ materially from those indicated by such forward-looking statements, including a deterioration in Aptevo's business or prospects; the inability to obtain, maintain or enforce intellectual property protection; further assessment of preliminary or interim data or different results from later studies; adverse events and unanticipated problems; adverse developments in clinical or preclinical development, including unexpected safety issues; constraints in radioisotope availability, manufacturing or supply; and changes in regulatory, social, macroeconomic and political conditions. Additional risks and factors that may affect results are set forth in Aptevo's filings with the SEC, including its Annual Report on Form 10-K for the year ended December 31, 2025, its subsequent report on Form 10-Q and current reports on Form 8-K. Any forward-looking statement speaks only as of the date of this press release, and, except as required by law, Aptevo does not assume any obligation to update any forward-looking statement to reflect new information, events or circumstances.</p><p><strong>Contact Information</strong></p><p>Miriam Weber Miller<br/>VP, Investor Relations & Corporate Communications<br/>Aptevo Therapeutics<br/>Email: <a rel="nofollow" href="mailto:IR@apvo.com">IR@apvo.com</a> or <a rel="nofollow" href="mailto:Millerm@apvo.com">Millerm@apvo.com</a><br/>Phone: 206-859-6628</p><p><strong>SOURCE:</strong> Aptevo Therapeutics</p><br/><br/>View the original <a href='https://www.accessnewswire.com/newsroom/en/healthcare-and-pharmaceutical/aptevo-therapeutics-announces-exercise-of-existing-warrants-and-pipe-1206482'>press release</a> on ACCESS Newswire<br/><br/>
      <img src="https://app.accessnewswire.com/img.ashx?id=1206482" width="0" height="0"/>

APVO

Aptevo Therapeutics Announces Exercise of Existing Warrants and PIPE for $4.5 Million Gross Proceeds

Aptevo raises about $4.5 million via warrant inducement and PIPE

<section class="insight" data-version="1">
  <section data-block="information">
    <h3>Information</h3>
    <p>SEATTLE, WA / ACCESS Newswire / August 12, 2026 / Aptevo Therapeutics Inc. (NASDAQ:APVO) (&amp;#34;Aptevo&amp;#34; or the &amp;#34;Company&amp;#34;), a clinical-stage biotechnology company developing novel multispecific immuno-oncology</p>
  </section>

  <section data-block="ai-summary-paragraph">
    <h3>AI Summary</h3>
    <p>Aptevo Therapeutics disclosed a financing package: warrant inducement agreements to cash-exercise 254,922 existing warrants at $4.03 and a PIPE to sell up to 861,708 shares plus 4,308,540 common warrants at $4.03, for gross proceeds of ~ $4.5 million. Proceeds are earmarked for working capital and the close is expected by August 13, 2026. The moves dilute existing holders but provide near-term liquidity to advance the company’s pipeline initiatives.</p>
  </section>

  <section data-block="ai-summary-bullets">
    <h3>Key Points</h3>
    <ul><li>Warrant inducement: exercise 254,922 shares at $4.03.</li><li>Inducement Warrants for 1,274,610 shares at $4.03.</li><li>PIPE raises up to 4.5M via 861,708 shares and 4,308,540 warrants at $4.03.</li><li>Close expected around Aug 13, 2026; proceeds for working capital.</li><li>Roth Capital Partners acts as exclusive placement agent.</li></ul>
  </section>

  <section data-block="companies-mentioned">
    <h3>Companies Mentioned</h3>
    <ul><li><strong>Aptevo Therapeutics (APVO)</strong>: Issuer of inducement and PIPE securities; near-term dilution risk; funds for working capital.</li><li><strong>Roth Capital Partners (ROTH)</strong>: Exclusive placement agent; facilitating private placement and related fees.</li></ul>
  </section>

  <section data-block="category">
    <h3>Corporate Developments</h3>
    <p>Corporate Developments: financing activity via warrants and a PIPE; potential dilution and near-term price dynamics, with liquidity support for pipeline work.</p>
  </section>

  <section data-block="market-moving">
    <h3>Market-Moving</h3>
    <ul><li>Warrant inducement and PIPE financing imply share dilution near-term.</li><li>Proposed close around August 13, 2026 could trigger price reaction.</li><li>Use of proceeds for working capital ties liquidity to execution of pipeline plans.</li></ul>
  </section>

  <section data-block="key-facts">
    <h3>Key Facts</h3>
    <ul><li>Proceeds expected ~$4.5 million gross.</li><li>Inducement warrants for 1,274,610 shares; exercisable after approval; 5-year term.</li><li>PIPE: up to 861,708 shares; 4,308,540 Common Warrants; price $4.03.</li><li>Close expected around August 13, 2026.</li><li>Roth Capital Partners is exclusive placement agent.</li></ul>
  </section>

  <section data-block="trading-thesis">
    <h3>Trading Thesis</h3>
    <p>Neutral near-term on APVO due to dilution; watch for Aug 13, 2026 close and use of proceeds.</p>
  </section>
</section>


<p><strong id="dateline">SEATTLE, WA / <a href='https://www.accessnewswire.com/'>ACCESS Newswire</a> / August 12, 2026 / </strong>Aptevo Therapeutics Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/quote/APVO">APVO</a>) ("Aptevo" or the "Company"), a clinical-stage biotechnology company developing novel multispecific immuno-oncology therapeutics, today announced it has entered into warrant inducement letter agreements with certain holders of its existing common warrants (the "Existing Warrants"), pursuant to which such holders have agreed to exercise in full for cash their Existing Warrants to purchase up to an aggregate of 254,922 shares of common stock of the Company ("common stock") at a reduced exercise price of $4.03 per share. In consideration for such cash exercises, the Company will issue new unregistered common stock purchase warrants (the "Inducement Warrants") to purchase up to an aggregate of 1,274,610 shares of common stock at an exercise price of $4.03 per share. The Inducement Warrants will be exercisable on or after the date on which the Company obtains the required stockholder approval and will expire five years after their initial exercise date. The shares of common stock issuable upon exercise of the Existing Warrants are registered pursuant to effective registration statements on Form S-1 (File No. 333-288061),Form S-1MEF (File No. 333-288134), Form S-3 (File No. 333-284969) and Form S-3 (File No. 333-283983).</p><p>Separately, pursuant to a securities purchase agreement, the Company agreed to sell to certain purchasers in a private placement (the "PIPE") up to 861,708 unregistered shares of common stock (the "Shares") at a purchase price of $4.03 per share (or, at a purchaser's election to comply with a 4.99% or 9.99% beneficial ownership limitation, pre-funded common stock purchase warrants (the "Pre-Funded Warrants") to purchase up to 861,708 shares in lieu of such shares), together with common stock purchase warrants (the "Common Warrants") to purchase up to 4,308,540 shares of common stock at an exercise price of $4.03 per share. The Pre-Funded Warrants will be exercisable immediately and will expire upon exercise in full, and the Common Warrants will be exercisable on or after the date on which the Company obtains the required stockholder approval and will expire five years after their initial exercise date (together, the "PIPE Warrants").</p><p>The aggregate gross proceeds from the transactions described herein are expected to total approximately $4.5 million, before deducting placement agent fees and expenses.</p><p>Roth Capital Partners, LLC is acting as the Company's exclusive placement agent in connection with these transactions.</p><p>The transactions are expected to close on or about August 13, 2026, subject to satisfaction of customary closing conditions. The Company intends to use the net proceeds from the transactions for working capital purposes.</p><p>The Inducement Warrants, the Shares, the Pre-Funded Warrants and the Common Warrants described above were offered in private placement transactions pursuant to Section 4(a)(2) of the Securities Act of 1933, as amended (the "1933 Act"), and Rule 506 promulgated thereunder, as applicable, and, along with the shares of common stock issuable upon exercise of the Inducement Warrants, the Pre-Funded Warrants and the Common Warrants, have not been registered under the 1933 Act and may not be offered or sold in the United States absent registration with the Securities and Exchange Commission ("SEC") or an applicable exemption from such registration requirements. The Company has agreed to file a registration statement with the SEC covering the resale of the Shares and the shares of common stock issuable upon exercise of the Inducement Warrants, the Pre-Funded Warrants and the Common Warrants.</p><p>This press release shall not constitute an offer to sell or a solicitation of an offer to buy nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or exemption under the securities laws of any such state or jurisdiction.</p><p><strong>About Aptevo Therapeutics</strong></p><p>Aptevo Therapeutics Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/quote/APVO">APVO</a>) is a clinical-stage biotechnology company developing novel multispecific immunotherapies for the treatment of cancer. The Company's lead clinical candidate, mipletamig, is currently being evaluated in frontline acute myeloid leukemia in combination with standard-of-care venetoclax + azacitidine. Aptevo's pipeline is generated from its proprietary ADAPTIR<sup>&#8482;</sup> and ADAPTIR-FLEX<sup>&#8482;</sup> platforms and includes bispecific and trispecific candidates designed to create multiple oncology value drivers across hematologic malignancies and solid tumors. In preclinical development, Aptevo is advancing APVO451, a nectin-4-targeted trispecific immunotherapy candidate for solid tumors and is pursuing strategic opportunities in radiopharmaceutical therapeutics to extend its tumor-targeting expertise into additional cancer treatment approaches. For more information, visit <a rel="nofollow" href="https://pr.report/f9pmaK8b"><strong>www.aptevotherapeutics.com</strong></a>.</p><p><strong>Cautionary Note Regarding Forward-Looking Statement</strong></p><p>This press release includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements, other than statements of historical fact, including, without limitation, statements regarding the closing of the transactions described herein, the satisfaction of the closing conditions of the transactions, the use of net proceeds from the transactions, and any other statements containing the words "may," "continue to," "believes," "knows," "expects," "optimism," "potential," "designed," "promising," "plans," "will" and similar expressions are intended to identify forward-looking statements. These forward-looking statements are based on Aptevo's current intentions, beliefs, and expectations regarding future events. Aptevo cannot guarantee that any forward-looking statement will be accurate. Investors should realize that if underlying assumptions prove inaccurate or unknown risks or uncertainties materialize, actual results could differ materially from Aptevo's expectations. Investors are, therefore, cautioned not to place undue reliance on any forward-looking statement.</p><p>There are several important factors that could cause Aptevo's actual results to differ materially from those indicated by such forward-looking statements, including a deterioration in Aptevo's business or prospects; the inability to obtain, maintain or enforce intellectual property protection; further assessment of preliminary or interim data or different results from later studies; adverse events and unanticipated problems; adverse developments in clinical or preclinical development, including unexpected safety issues; constraints in radioisotope availability, manufacturing or supply; and changes in regulatory, social, macroeconomic and political conditions. Additional risks and factors that may affect results are set forth in Aptevo's filings with the SEC, including its Annual Report on Form 10-K for the year ended December 31, 2025, its subsequent report on Form 10-Q and current reports on Form 8-K. Any forward-looking statement speaks only as of the date of this press release, and, except as required by law, Aptevo does not assume any obligation to update any forward-looking statement to reflect new information, events or circumstances.</p><p><strong>Contact Information</strong></p><p>Miriam Weber Miller<br/>VP, Investor Relations & Corporate Communications<br/>Aptevo Therapeutics<br/>Email: <a rel="nofollow" href="mailto:IR@apvo.com">IR@apvo.com</a> or <a rel="nofollow" href="mailto:Millerm@apvo.com">Millerm@apvo.com</a><br/>Phone: 206-859-6628</p><p><strong>SOURCE:</strong> Aptevo Therapeutics</p><br/><br/>View the original <a href='https://www.accessnewswire.com/newsroom/en/healthcare-and-pharmaceutical/aptevo-therapeutics-announces-exercise-of-existing-warrants-and-pipe-1206482'>press release</a> on ACCESS Newswire<br/><br/>
      <img src="https://app.accessnewswire.com/img.ashx?id=1206482" width="0" height="0"/>

Aptevo Therapeutics disclosed a financing package: warrant inducement agreements to cash-exercise 254,922 existing warrants at $4.03 and a PIPE to sell up to 861,708 shares plus 4,308,540 common warrants at $4.03, for gross proceeds of ~ $4.5 million. Proceeds are earmarked for working capital and the close is expected by August 13, 2026. The moves dilute existing holders but provide near-term liquidity to advance the company’s pipeline initiatives.

News insight

Aptevo Therapeutics Announces Exercise of Existing Warrants and PIPE for $4.5 Million Gross Proceeds

AI summary

Sentiment rationale

Key facts

Corporate Developments