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CalciMedica Announces Appointment of Dr. Alan Glicklich to Board of Directors

1. Alan Glicklich appointed to CalciMedica Board of Directors effective January 15, 2025. 2. Glicklich brings 20+ years of experience in biotechnology and clinical development. 3. His expertise will aid CalciMedica's trials for Auxora in acute diseases. 4. Auxora shows positive effects on organ failure in clinical trials. 5. CalciMedica aims to address urgent needs in inflammatory disease therapies.

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Why Bullish?

The appointment of a seasoned expert generally boosts investor confidence, similar to other biotech firms who saw price increases after adding experienced board members.

How important is it?

This article highlights a key personnel change that is likely to positively steer the company's strategic direction and clinical capabilities, adding weight to investor outlook.

Why Long Term?

The influence of Glicklich's expertise will unfold as the company's clinical trials mature, reflecting oversight dynamically on future results.

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CALCNUVGCHKPBIRDARENA
, /PRNewswire/ -- CalciMedica Inc. ("CalciMedica" or the "Company") (Nasdaq: CALC), a clinical-stage biopharmaceutical company focused on developing novel calcium release-activated calcium (CRAC) channel inhibition therapies for acute and chronic inflammatory and immunologic illnesses, today announced the appointment of Alan Glicklich, M.D. to the Company's Board of Directors effective on January 15, 2025. Dr. Glicklich has more than 20 years of experience in the biotechnology industry and currently serves as Chief Medical Officer of Nuvig Therapeutics. "We are very pleased to welcome Alan to our Board and excited to benefit from his extensive clinical development experience and impressive track record working with biotech and pharma companies, specifically in the inflammatory and immunologic disease spaces," said Rachel Leheny, Ph.D., Chief Executive Officer of CalciMedica. "As we progress Auxora towards a Phase 3 trial in acute pancreatitis and look ahead to data from our KOURAGE trial in acute kidney injury, Alan's perspective will be extremely valuable to CalciMedica." In his position at Nuvig Therapeutics, a company pursuing multiple inflammatory autoimmune diseases, Dr. Glicklich is currently leading a clinical team planning to initiate multiple Phase 2 trials. Prior to Nuvig, Dr. Glicklich was Chief Medical Officer of Chinook Therapeutics, where he was responsible for the clinical development, clinical operations, medical affairs, biometrics, regulatory, and pharmacovigilance teams. While at Chinook, he designed and operationalized a successful Phase 3 registrational study for atrasentan in IgA nephropathy as well as multiple earlier phase studies across rare chronic kidney disease indications. Before that, Dr. Glicklich was Chief Medical Officer at Bird Rock Bio, where he focused on monoclonal antibody development for inflammatory and fibrotic diseases. Prior to Bird Rock, he was Vice President of Clinical Development at Arena Pharmaceuticals, where he designed and operationalized two Phase 2 programs in pulmonary arterial hypertension and ulcerative colitis. Dr. Glicklich has also held positions at BMS, Sanofi-Aventis, and Regeneron. Dr. Glicklich holds an M.D. from the University of Wisconsin and an M.B.A. from the Emory University-Goizueta School of Business, as well as a B.A. in Biology from the University of Chicago. "I am impressed by the data from the multiple Phase 2 clinical trials with CalciMedica's drug, Auxora, which has shown a variety of benefits, including a substantial reduction in organ failure, in acute inflammatory diseases. These benefits are important to patients in CalciMedica's lead indications of acute pancreatitis and acute kidney injury, in which organ failure is a significant cause of mortality and morbidity, no disease-modifying therapies are available, and the standard of care is inadequate. I look forward to working with the team at CalciMedica to bring these much-needed therapies to patients," said Dr. Glicklich. About CalciMedicaCalciMedica is a clinical-stage biopharmaceutical company focused on developing novel CRAC channel inhibition therapies for inflammatory and immunologic diseases. CalciMedica's proprietary technology targets the inhibition of CRAC channels to modulate the immune response and protect against tissue cell injury, with the potential to provide therapeutic benefits in life-threatening inflammatory and immunologic diseases for which there are currently no approved therapies. CalciMedica's lead product candidate Auxora™ has demonstrated positive and consistent clinical results in multiple completed efficacy clinical trials. CalciMedica has announced data for a Phase 2b trial (called CARPO – NCT04681066) in patients with acute pancreatitis (AP) and accompanying systemic inflammatory response syndrome (SIRS). The Company has also completed a Phase 2 trial (called CARDEA – NCT04345614) in patients with COVID pneumonia. The Company is currently conducting a Phase 2 trial (called KOURAGE – NCT06374797) in patients with acute kidney disease (AKI) with associated acute hypoxemic respiratory failure (AHRF) with data expected in 2025 and continuing to support the ongoing Phase 1/2 trial (called CRSPA – NCT04195347) in pediatric patients with asparaginase-induced pancreatic toxicity (AIPT) with data expected in 2025. CalciMedica was founded by scientists from Torrey Pines Therapeutics and the Harvard CBR Institute for Biomedical Research, and is headquartered in La Jolla, CA. For more information, please visit www.calcimedica.com. Forward-Looking StatementsThis communication contains forward-looking statements which include, but are not limited to,  CalciMedica's ongoing and planned clinical trials and the timing and design thereof, including its plans to progress a Phase 3 trial of Auxora in AP, and the expected timing for the release of data from those trials, including its ongoing Phase 1/2 CRSPA trial of Auxora in pediatric patients with AIPT and its ongoing Phase 2 KOURAGE trial of Auxora in AKI with associated AHRF; the potential benefits of Auxora for the treatment of AP, AKI and AIPT; and the potential of CalciMedica's proprietary technology to provide therapeutic benefits in life-threatening inflammatory and immunologic diseases. These forward-looking statements are subject to the safe harbor provisions under the Private Securities Litigation Reform Act of 1995. CalciMedica's expectations and beliefs regarding these matters may not materialize. Actual outcomes and results may differ materially from those contemplated by these forward-looking statements as a result of uncertainties, risks, and changes in circumstances. Risks and uncertainties that could cause actual outcomes and results to differ materially from those contemplated by the forward-looking statements are included under the caption "Risk Factors" in CalciMedica's Quarterly Report on Form 10-Q for the quarter ended September 30, 2024, filed with the U.S. Securities and Exchange Commission (SEC) on November 13, 2024, and elsewhere in CalciMedica's subsequent reports on Form 10-K, Form 10-Q or Form 8-K filed with the SEC from time to time and available at www.sec.gov. These documents can be accessed on CalciMedica's web page at ir.calcimedica.com/financials-filings/sec-filings. The forward-looking statements contained herein are made as of the date hereof, and CalciMedica undertakes no obligation to update them after this date, except as required by law. CalciMedica Contact: Investors and MediaArgot PartnersSarah Sutton/Kevin Murphy[email protected](212) 600-1902 SOURCE CalciMedica, Inc. WANT YOUR COMPANY'S NEWS FEATURED ON PRNEWSWIRE.COM? 440k+ Newsrooms & Influencers 9k+ Digital Media Outlets 270k+ Journalists Opted In

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