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Benzinga
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Cassava Sciences Discontinues Developing Simufilam For Alzheimer's After Another Phase 3 Trial Flop

1. Cassava's Phase 3 REFOCUS-ALZ study results were disappointing. 2. Simufilam did not meet cognitive and functional endpoints. 3. The drug development program for Alzheimer's will be terminated. 4. Cassava plans to phase out the Alzheimer's program by Q2 2025. 5. Stock declined 22.1%, reflecting market disappointment.

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FAQ

Why Very Bearish?

Failure in Phase 3 trials typically leads to sharp stock declines, as seen with biopharmaceutical firms like Anavex Life Sciences post-trial failures.

How important is it?

The failed trial outcome provides critical insights into simufilam's potential viability, affecting investor confidence and market positioning.

Why Short Term?

Investors are likely to react swiftly to trial failures, impacting stock price immediately and over the next few trading sessions.

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