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Conditional Issuance of Shares

1. Nyxoah announces conditional issuance of up to 5 million shares. 2. Total shares available under ATM program reaches approximately 5.66 million. 3. Shares will sell at prevailing market prices on Nasdaq. 4. Issuance may dilute existing shareholder equity. 5. No immediate financial offer is made in the announcement.

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FAQ

Why Bearish?

Issuing new shares typically dilutes existing equity, potentially lowering share value. Historical instances show price drops after similar announcements due to market reaction.

How important is it?

The announcement of share issuance is significant as it directly impacts share value and ownership structure, influencing investor sentiment and market perception.

Why Short Term?

The immediate market reaction to share dilution will likely occur shortly after the announcement. Historical data supports notable price adjustments in the days following new share issuance.

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INSIDE INFORMATIONREGULATED INFORMATION Conditional Issuance of Shares Mont-Saint-Guibert, Belgium – April 16, 2025, 8:00 am CET / 2:00 am ET – Nyxoah SA (Euronext Brussels/Nasdaq: NYXH) (“Nyxoah” or the “Company”), today announced a conditional issuance of up to 5 million ordinary shares under its existing at-the-market equity offering programs (the “ATM”). This brings the aggregate number of ordinary shares that can be sold and issued under the Company’s ATM to 5,662,694 (the “ATM Shares”), which includes 662,694 shares that are still available from the conditional issuance of shares under the ATM decided upon on December 22, 2022. Pursuant to the existing sales agreement entered into by the Company on December 22, 2022, ATM Shares may be sold from time to time at a sales price per ATM Share equal to prevailing USD market prices of the Nyxoah ordinary share on the Nasdaq Global Market at the time of the sale. This press release shall not constitute an offer to sell or a solicitation of an offer to buy any securities. Contacts: NyxoahJohn Landry, CFOIR@nyxoah.com ATM PR - ENG - FINAL

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