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Fractyl Health to Report Fourth Quarter and Full Year 2024 Financial Results and Provide Business Updates on March 3, 2025

1. GUTS to report Q4 and 2024 results on March 3, 2025. Webcast available live and replay. 2. Focus remains on metabolic therapies for obesity and type 2 diabetes. Innovative approach emphasized. 3. Event provides critical business updates and financial performance insights. Investors encouraged to monitor webcast. 4. Scheduled earnings may trigger short-term price volatility. Market reactions to updates will be pivotal.

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Why Neutral?

Earnings report events typically cause temporary volatility but no intrinsic shift in fundamentals. Historical biotech earnings have shown similar transient market movements without lasting directional change.

How important is it?

Earnings announcements are pivotal events that can trigger immediate trading decisions, making them highly relevant. The event may significantly influence investor perceptions if results diverge from expectations.

Why Short Term?

Earnings and business updates directly influence near-term trading sentiment and volatility. Similar events in the past have led to quick price adjustments until longer-term guidance emerges.

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BURLINGTON, Mass., Feb. 24, 2025 (GLOBE NEWSWIRE) -- Fractyl Health, Inc. (Nasdaq: GUTS) (the “Company”), a metabolic therapeutics company focused on pioneering pattern breaking approaches for the treatment of obesity and type 2 diabetes (T2D), today announced it will report financial results for the fourth quarter and full year 2024 and provide business updates on Monday, March 3, 2025, at 4:30 p.m. ET. A live webcast of the conference call can be accessed in the “Events” section of Fractyl’s website at https://ir.fractyl.com/. The webcast will be archived and available for replay following the live event. About Fractyl Health Fractyl Health is a metabolic therapeutics company focused on pioneering new approaches to the treatment of metabolic diseases, including obesity and T2D. Despite advances in treatment over the last 50 years, obesity and T2D continue to be rapidly growing drivers of morbidity and mortality in the 21st century. Fractyl Health’s goal is to transform metabolic disease treatment from chronic symptomatic management to durable disease-modifying therapies that target the organ-level root causes of disease. Fractyl Health is based in Burlington, MA. For more information, visit www.fractyl.com. Contacts  Media Contact Jessica Cotrone, Head of Corporate Communicationsjcotrone@fractyl.com. 978.760.5622 Investor ContactBrian Luque, Head of Investor Relations and Corporate DevelopmentIR@fractyl.com, 951.206.1200

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