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KEYTRUDA® (pembrolizumab) plus Padcev® (enfortumab vedotin-ejfv) Significantly Improved Event-Free and Overall Survival and Pathologic Complete Response Rate for Certain Patients with Muscle-Invasive Bladder Cancer When Given Before and After Surgery

1. MRK's KEYTRUDA shows positive results in muscle-invasive bladder cancer treatment. 2. Significant efficacy improves MRK's competitive position in cancer therapies.

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Why Bullish?

The positive trial results enhance MRK's oncology portfolio, potentially boosting sales. Historically, successful clinical trials can lead to stock price increases, as seen with previous oncology drug approvals.

How important is it?

The article discusses a significant milestone in cancer treatment which can greatly impact MRK's market position and revenue trajectory, emphasizing its importance in the healthcare sector.

Why Long Term?

If approved, these results can lead to market traction and revenue growth over several years, akin to past successes in cancer treatments which showed sustained market performance post-approval.

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RAHWAY, N.J.--(BUSINESS WIRE)--Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced positive topline results from the Phase 3 KEYNOTE-905 trial (also known as EV-303) in patients with muscle-invasive bladder cancer (MIBC) who are ineligible for cisplatin-based chemotherapy. In this study, KEYTRUDA® (pembrolizumab) plus Padcev (enfortumab vedotin-ejfv), given before and after surgery (radical cystectomy), demonstrated a statistically significant and clinically me.

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