Novartis Breaks Ground on Flagship Manufacturing Hub in North Carolina
On December 12, 2025, Novartis (NVS) announced the groundbreaking of its new flagship manufacturing hub in North Carolina, representing a significant investment in both the local economy and the U.S. healthcare system. This manufacturing facility will enhance Novartis's capacity to produce key medicines domestically, fulfilling its commitment to strengthening the U.S. supply chain.
Details of the New Manufacturing Hub
The new hub will feature a state-of-the-art facility in Morrisville and additional sites in Durham. This expansion includes construction of two new manufacturing facilities, alongside an expansion of Novartis's existing facility in Durham. Together, these developments are projected to create 700 new jobs in North Carolina by 2030, while supporting over 3,000 indirect jobs throughout the Novartis U.S. supply chain.
CEO Vas Narasimhan remarked, “It’s an exciting day for Novartis as we break ground on our new manufacturing hub, a crucial step toward delivering on our goal of producing all our key medicines for U.S. patients domestically.” He emphasized that this hub will become a central manufacturing site for Novartis in the U.S., further strengthening their supply chain.
Economic Impact and Local Support
The groundbreaking ceremony was attended by notable figures, including FDA Commissioner Marty Makary and North Carolina Governor Josh Stein, highlighting the hub's potential impact on U.S. patients and the local economy. Governor Stein said, “These investments bring in more good-paying jobs for North Carolinians and build a stronger, more resilient supply chain for patients across the country.”
The project is part of Novartis's broader strategy, with a planned $23 billion investment in U.S.-based infrastructure over the next five years. This significant allocation is aimed at enhancing production and research capabilities across the nation.
Future Plans and Regulatory Milestones
Expected to be operational by 2027-2028, the new manufacturing hub signifies Novartis's ongoing commitment to innovation and expansion in the pharmaceutical sector. This year alone, the company has achieved five FDA approvals across various therapeutic areas, including oncology and neuroscience, reinforcing its dedication to delivering groundbreaking treatments to U.S. patients.
- New $1.1 billion biomedical research hub in San Diego, CA.
- Expansion of existing facilities in Indiana and New Jersey.
- New manufacturing facilities planned for Florida and Texas, reinforcing a coast-to-coast radioligand therapy network.
- End-to-end manufacturing capabilities for all key medicines for U.S. patients.
Commitment to American Patients
As a company that places significant importance on the U.S. market, Novartis (NVS) is focused on developing innovative treatments while simultaneously driving local job creation and economic growth. The firm is dedicated to ensuring that critical medicines are accessible to U.S. patients while reinforcing its foundation within the community.
FDA Commissioner Makary highlighted the initiative's alignment with national security and the America First agenda, stating, “Novartis’s investment is a strong step toward making drugs for Americans in America.”
About Novartis
Novartis is a global leader in innovative medicines, dedicated to improving and extending patients’ lives through advanced healthcare solutions. The company reaches nearly 300 million people worldwide with its medicines.