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OptimizeRx Reports First Quarter 2025 Financial Results and Updates Fiscal Year 2025 Guidance

1. Q1 revenue reached $21.9 million, up 11% year-over-year. 2. Gross profit increased 9% year-over-year to $13.3 million. 3. Full-year 2025 revenue guidance raised to $101-$106 million. 4. Non-GAAP net income achieved of $1.5 million, a significant improvement. 5. Contracted revenue increased over 20% year-to-date compared to last year.

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Why Bullish?

Q1 revenue and profit growth signals strong operational momentum; past performance trends, such as similar revenue increases leading to stock price gains, indicate positive investor sentiment.

How important is it?

The positive earnings report and raised guidance could significantly enhance investor confidence and increase stock value.

Why Short Term?

Immediate investor responses are expected as the company meets or exceeds forecast; momentum could wan rapidly if projections falter.

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XLRNIQVRMD
Q1 revenue of $21.9 million, increasing 11% year-over-yearQ1 gross profit increased 9% year-over-year to $13.3 millionIncreases full year 2025 guidance to a revenue range between $101 million and $106 million and adjusted EBITDA range between $13 million and $15 million WALTHAM, Mass., May 12, 2025 (GLOBE NEWSWIRE) -- OptimizeRx Corp. (the “Company”) (Nasdaq: OPRX), a leading provider of healthcare technology solutions helping life sciences companies reach and engage healthcare professionals (HCPs) and patients, today reported results for the three months ended March 31, 2025. Quarterly comparisons are to the same year-ago period. Financial Highlights Revenue in the first quarter of 2025 increased 11% to $21.9 million, as compared to $19.7 million in the same year ago periodGross profit in the first quarter of 2025 increased 9% year-over-year to $13.3 million, from $12.2 million during the first quarter of 2024GAAP net loss totaled $(2.2) million or $(0.12) per basic and diluted share in the first quarter of 2025, as compared to $(6.9) million or $(0.38) per basic and diluted share during the first quarter of 2024Non-GAAP net income in the first quarter totaled $1.5 million or $0.08 per diluted share, as compared to Non-GAAP net loss of $(2.0) million or $(0.11) per diluted share during the first quarter of 2024 (see *Non-GAAP Measures below)Adjusted EBITDA for the first quarter of 2025 increased to $1.5 million compared to $(0.3) million in the same year ago period (see *Non-GAAP Measures below)Cash, cash equivalents and short-term investments totaled $16.6 million as of March 31, 2025, as compared to $13.4 million as of December 31, 2024 Stephen L. Silvestro, OptimizeRx CEO commented, “I’m encouraged by our year-to-date performance, which has exceeded both consensus estimates and our internal expectations. The momentum we saw at the end of 2024 has carried into 2025, with year-to-date contracted revenue up more than 20% compared to the same period last year—positioning us well for a strong second half of the year. I believe this performance clearly reflects the results of our focus on operational excellence, our commitment to delighting customers, and our efforts to deepen relationships with valued business partners, all of which are driving meaningful shareholder value. “At the same time, we’ve already converted over 5% of our expected 2025 sales into subscription-based revenue streams. I believe this transition, combined with our improving operating leverage, puts us on a strong path toward achieving Rule of 40 performance in the coming years. “Given our strong performance and positive outlook, I’m pleased to announce that we are raising our full-year guidance. We now expect the revenue range to be between $101 million and $106 million, and adjusted EBITDA to be between $13 million and $15 million.”  Rolling Twelve Months Ended March 31,Key Performance Indicators (KPIs)** 2025   2024  (in thousands, except percentages)Average revenue per top 20 pharmaceutical manufacturer$2,960  $2,592 Percent of total revenue attributable to top 20 pharmaceutical manufacturers 63%  66%Net revenue retention 114%  116%Revenue per average full-time employee$710  $641  2025 Financial Outlook The Company is increasing its 2025 guidance and expects revenue to be between $101 million and $106 million with Adjusted EBITDA to be between $13 million and $15 million. Conference Call Date: Monday, May 12, 2025Time: 4:30 p.m. Eastern Time (1:30 p.m. Pacific Time)Toll Free: 1-844-825-9789International:   1-412-317-5180Conference ID: 10198829Call Me: https://callme.viavid.com/?$Y2FsbG1lPXRydWUmcGFzc2NvZGU9JmluZm89Y29tcGFueSZyPXRydWUmYj0xNg==Webcast: https://viavid.webcasts.com/starthere.jsp?ei=1708545&tp_key=86684771bfCall Me Passcode: 8199416Webcast Replay: The archived webcast will be on the investor relations section of the OptimizeRx website Individual Meeting Invitation In an effort to increase relations with institutional investors, OptimizeRx management has dedicated time to hosting individual meetings with portfolio managers and analysts. If you are interested in scheduling a meeting with OptimizeRx management, please contact: adsilva@optimizerx.com or shalper@lifesciadvisors.com. *Non-GAAP Measures In addition to the financial measures prepared in accordance with generally accepted accounting principles (GAAP), this earnings release also contains non-GAAP financial measures. The reasons why we believe these measures provide useful information to investors and, for historical periods, a reconciliation of these measures to the most directly comparable GAAP measures are included in the supplemental tables that follow. Although the Company provides guidance for Adjusted EBITDA, a non-GAAP financial measure, it is not able to provide guidance to the most directly comparable GAAP measure. Reconciliations for forward-looking figures would require unreasonable effort at this time because of the uncertainty and variability of the nature and amount of certain components of various necessary GAAP components, including, for example, those related to compensation, acquisition expenses, other income, amortization or others that may arise during the year, and the Company’s management believes such reconciliations would imply a degree of precision that would be confusing or misleading to investors. For the same reasons, the Company is unable to address the probable significance of the unavailable information. **Definition of Key Performance Indicators Top 20 pharmaceutical manufacturers: We have updated the definition of “top 20 pharmaceutical manufacturers” in our key performance indicators to be based upon Fierce Pharma’s most updated list of “The top 20 pharma companies by 2024 revenue”. We previously used “The top 20 pharma companies by 2023 revenue”. As a result of this change, prior periods have been restated for comparative purposes. Net revenue retention: Net revenue retention is a comparison of revenue generated from all clients in the previous period to total revenue generated from the same clients in the following year (i.e., excludes new client relationships for the most recent year). Revenue per average full-time employee: We define revenue per average full-time employee (FTE) as total revenue over the last 12 months (LTM) divided by the average number of employees over the LTM, which is calculated by taking our total number of FTEs at the end of the prior year period by our total FTE headcount at the end of the most recent period. About OptimizeRx OptimizeRx is a leading healthcare technology company that’s redefining how life science brands connect with patients and healthcare providers. Our platform combines innovative AI-driven tools like the Dynamic Audience Activation Platform (DAAP) and Micro-Neighborhood Targeting (MNT) to deliver timely, relevant, and hyper-local engagement. By bridging the gap between HCP and DTC strategies, we empower brands to create synchronized marketing solutions that drive faster treatment decisions and improved patient outcomes. Our commitment to privacy-safe, patient-centric technology ensures that every interaction is designed to make a meaningful impact, delivering life-changing therapies to the right patients at the right time. Headquartered in Waltham, Massachusetts, OptimizeRx partners with some of the world’s leading pharmaceutical and life sciences companies to transform the healthcare landscape and create a healthier future for all. For more information, follow the Company on Twitter, LinkedIn or visit www.optimizerx.com.   Important Cautions Regarding Forward-Looking Statements This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Words such as “anticipates”, “believes”, “estimates”, “expects”, “forecasts”, “intends”, “plans”, “projects”, “targets”, “designed”, “could”, “may”, “should”, “will” or other similar words and expressions are intended to identify these forward-looking statements. All statements that reflect the Company’s expectations, assumptions, projections, beliefs or opinions about the future, other than statements of historical fact, are forward-looking statements, including, without limitation, statements relating to the Company’s future performance, expected revenues, expected Adjusted EBITDA, plans to grow shareholder value creation, plans to continue the Company’s growth and transformation, plans to position the Company to become a “Rule of 40” company, plans for forging stronger relationships with valued business partners, and other statements relating to future performance, plans, and expectations. These forward-looking statements are based on the Company’s current expectations and involve assumptions regarding the Company’s business, the economy, and other future conditions that may never materialize or may prove to be incorrect. Forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted, or quantified. Actual results and the timing of events could differ materially from those anticipated in such forward-looking statements as a result of various risks and uncertainties including, but not limited to, the effect of government regulation, seasonal trends, dependence on a concentrated group of customers, cybersecurity incidents that could disrupt operations, the ability to keep pace with growing and evolving technology, the ability to maintain contracts with electronic prescription platforms and electronic health records networks, competition, and other factors discussed in the Company’s Annual Report on Form 10-K for the fiscal year ended December 31, 2024, its subsequent Quarterly Reports on Form 10-Q, and in other filings the Company has made and may make with the Securities and Exchange Commission in the future. One should not place undue reliance on these forward-looking statements, which speak only as of the date on which they were made. The Company undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made, except as may be required by law. OptimizeRx ContactAndy D’Silva, SVP Corporate Financeadsilva@optimizerx.com Investor Relations ContactSteven HalperLifeSci Advisors, LLCshalper@lifesciadvisors.com OPTIMIZERX CORPORATIONCONDENSED CONSOLIDATED BALANCE SHEETS (in thousands, except share and per share data)  March 31,2025 December 31,2024ASSETS(unaudited)  Current assets   Cash and cash equivalents$16,573  $13,380 Accounts receivable, net of allowance for credit losses of $335 at March 31, 2025 and December 31, 2024 32,720   38,212 Taxes receivable 113   — Prepaid expenses and other 2,305   2,379 Total current assets 51,711   53,971 Property and equipment, net 150   150 Other assets   Goodwill 70,869   70,869 Patent rights, net 5,349   5,517 Technology assets, net 7,931   8,180 Tradename and customer relationships, net 31,226   31,819 Operating lease right of use assets 303   366 Security deposits and other assets 229   296 Total other assets 115,907   117,047 TOTAL ASSETS$167,768  $171,168     LIABILITIES AND STOCKHOLDERS’ EQUITY    Current liabilities   Current portion of long-term debt$3,300  $2,000 Accounts payable 3,381   2,156 Accrued expenses 9,277   8,486 Revenue share payable 1,743   5,053 Taxes payable —   318 Current portion of lease liabilities 139   168 Deferred revenue 511   473 Total current liabilities 18,351   18,654 Non-current liabilities   Long-term debt, net 29,190   30,816 Lease liabilities, net of current portion 171   209 Deferred tax liabilities, net 3,786   4,491 Total liabilities 51,498   54,170     Stockholders’ equity   Preferred stock, $0.001 par value, 10,000,000 shares authorized, none issued and outstanding at March 31, 2025 or December 31, 2024 —   — Common stock, $0.001 par value, 166,666,667 shares authorized, 20,234,186 and 20,194,697 shares issued at March 31, 2025 and December 31, 2024, respectively 20   20 Treasury stock, $0.001 par value, (1,741,397) shares held at March 31, 2025 and December 31, 2024 (2)  (2)Additional paid-in-capital 202,819   201,348 Accumulated deficit (86,567)  (84,368)Total stockholders’ equity 116,270   116,998 TOTAL LIABILITIES AND STOCKHOLDERS’ EQUITY$167,768  $171,168   OPTIMIZERX CORPORATIONCONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS (in thousands, except share and per share data, unaudited)  For the Three Months EndedMarch 31,  2025   2024     Net revenue$21,928  $19,690 Cost of revenues, exclusive of depreciation and amortization presented separately below 8,584   7,486 Gross profit 13,344   12,204     Operating expenses   General and administrative expenses 14,364   16,166 Depreciation and amortization 1,094   1,067 Total operating expenses 15,458   17,233 Loss from operations (2,114)  (5,029)Other income (expense)   Interest expense (1,297)  (1,546)Other income 39   — Interest income 88   20 Total other expense, net (1,170)  (1,526)Loss before provision for income taxes (3,284)  (6,555)Income tax benefit (expense) 1,085   (344)Net loss$(2,199) $(6,899)Weighted average number of shares outstanding – basic 18,470,808   18,170,108 Weighted average number of shares outstanding – diluted 18,470,808   18,170,108 Loss per share – basic$(0.12) $(0.38)Loss per share – diluted$(0.12) $(0.38)  OPTIMIZERX CORPORATIONCONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS(in thousands, unaudited)  For the Three Months EndedMarch 31, 2025 2024CASH FLOWS FROM OPERATING ACTIVITIES:   Net loss$(2,199) $(6,899)Adjustments to reconcile net loss to net cash provided by operating activities:   Depreciation and amortization 1,094   1,067 Stock-based compensation 1,558   3,024 Bad debt reserve —   132 Amortization of debt issuance costs 174   182 Changes in:   Accounts receivable 5,492   6,373 Prepaid expenses and other assets 74   800 Accounts payable 1,225   (562)Revenue share payable (3,310)  (2,692)Accrued expenses and other liabilities 854   (362)Taxes receivable and payable (431)  323 Deferred tax liabilities (705)  — Deferred revenue 38   732 NET CASH PROVIDED BY OPERATING ACTIVITIES 3,864   2,118     CASH FLOWS USED IN INVESTING ACTIVITIES:   Purchase of property and equipment (27)  (32)Capitalized software development costs (57)  (121)NET CASH USED IN INVESTING ACTIVITIES (84)  (153)    CASH FLOWS USED IN FINANCING ACTIVITIES:   Cash paid for employee withholding taxes related to the vesting of restricted stock units (87)  (140)Repayment of long-term debt (500)  (500)NET CASH USED IN FINANCING ACTIVITIES (587)  (640)NET INCREASE IN CASH AND CASH EQUIVALENTS 3,193   1,325 CASH AND CASH EQUIVALENTS - BEGINNING OF PERIOD 13,380   13,852 CASH AND CASH EQUIVALENTS - END OF PERIOD$16,573  $15,177     SUPPLEMENTAL CASH FLOW INFORMATION:   Cash paid for interest$1,121  $1,350 Cash paid for income taxes$—  $21  OPTIMIZERX CORPORATIONRECONCILIATION of GAAP to NON-GAAP FINANCIAL MEASURES(in thousands, except share and per share data, unaudited) This earnings release includes certain financial measures not derived in accordance with generally accepted accounting principles (GAAP). These non-GAAP financial measures are measures of performance not defined by accounting principles generally accepted in the United States and should be considered in addition to, not in lieu of, GAAP reported measures. Additionally, these non-GAAP measures may not be comparable to similarly titled measures reported by other companies. However, management believes that presenting certain non-GAAP financial measures provides additional information to facilitate comparison of the Company's historical operating results and trends in its underlying operating results and provides transparency on how the Company evaluates its business. Management uses these non-GAAP financial measures in making financial, operating and planning decisions and in evaluating the Company's performance. Management believes that financial information excluding certain items that are not considered to reflect the Company’s ongoing operating results, such as those listed below, improves the comparability of year-to-year results. Consequently, management believes that investors may be able to better understand the Company’s operating results excluding these items. Non-GAAP financial measures may reflect adjustments for items such as asset impairment charges, amortization, stock-based compensation, acquisition expenses, severance, shareholder activist related fees, CEO search fees, other income, as well as other items that management believes are not related to the Company’s ongoing performance.  Three Months Ended March 31,  2025   2024 Net loss$        (2,199) $        (6,899)Depreciation and amortization         1,094           1,067 Stock-based compensation         1,558           3,024 Severance expenses         275           419 Shareholder activist related fees         451           — CEO search fees         225           — Other income         (39)          — Amortization of debt issuance costs         174           182 Acquisition expenses         —           243 Non-GAAP net income (loss)$        1,539  $        (1,964)    Non-GAAP net income (loss) per share   Diluted$        0.08  $        (0.11)Weighted average shares outstanding:   Diluted 18,579,012   18,170,108   Three Months Ended March 31, 2025 2024Net loss$(2,199) $(6,899)Depreciation and amortization 1,094   1,067 Income tax (benefit) expense (1,085)  344 Stock-based compensation 1,558   3,024 Severance expenses 275   419 Acquisition expenses —   243 Shareholder activist related fees 451   — CEO search fees 225   — Other income (39)  — Interest expense, net 1,209   1,526 Adjusted EBITDA$1,489  $(276)

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