Sanofi Announces Acquisition of Dynavax to Expand Vaccine Portfolio
On December 24, 2025, Sanofi (NASDAQ: SNY) revealed its agreement to acquire Dynavax Technologies Corporation, a leading publicly traded vaccines company known for its adult hepatitis B vaccine, HEPLISAV-B®, and a promising shingles vaccine candidate currently in development. This strategic acquisition enhances Sanofi's position in the adult immunization market, combining Dynavax’s innovative vaccine portfolio with Sanofi's extensive global reach and developmental capabilities.
HEPLISAV-B®: A Key Asset in the Acquisition
Dynavax's HEPLISAV-B® sets itself apart as it offers a two-dose regimen administered over one month, ensuring rapid seroprotection levels compared to traditional hepatitis B vaccines that require three doses over six months. This remarkable feature positions HEPLISAV-B® as a vital component in meeting the rising demand for effective vaccines in the adult population.
Shingles Vaccine Candidate and Future Prospects
The acquisition also includes Dynavax’s shingles vaccine candidate, Z-1018, which is currently in phase 1/2 clinical trials, along with additional vaccine pipeline projects. Thomas Triomphe, Executive Vice President of Vaccines at Sanofi, stated, “Dynavax enhances Sanofi’s adult immunization presence by adding differentiated vaccines that complement Sanofi’s expertise.” This reinforces Sanofi’s commitment to providing comprehensive vaccine protection for adults.
The Public Health Imperative
Vaccines for hepatitis B and shingles address significant public health needs in the US, where about 100 million adults born before 1991 remain unvaccinated. Chronic hepatitis B infections can lead to severe liver complications, while shingles can cause painful rashes and long-lasting nerve pain. These conditions not only affect individual health but also represent substantial public health challenges that Sanofi aims to mitigate through this acquisition.
Financial Overview of the Acquisition
Under the terms of the merger agreement, Sanofi will initiate a cash tender offer of $15.50 per share for all outstanding shares of Dynavax, valuing the transaction at approximately $2.2 billion. The deal has garnered unanimous approval from Dynavax's board of directors and is set to fulfill customary closing conditions, including required regulatory approvals.
- Cash tender offer at $15.50 per share
- Total equity value of approximately $2.2 billion
- Expected completion in Q1 2026, pending regulatory and shareholder approvals
Maintaining Financial Stability
Sanofi projects that this acquisition will not influence its financial guidance for 2025. The company intends to finance the acquisition through available cash resources, thus maintaining financial stability as they integrate Dynavax's innovative offerings into their existing portfolio.
About Sanofi and Dynavax
Sanofi is a research-driven biopharmaceutical company focused on developing advanced medicines and vaccines across various therapeutic fields. With a commitment to tackling urgent healthcare challenges, Sanofi actively contributes to public health through innovation.
Dynavax is a biopharmaceutical firm dedicated to designing and commercializing vaccines that protect against infectious diseases. Its HEPLISAV-B® vaccine is currently marketed in the US and Europe, reflecting the company’s dedication to advancing vaccine technology.