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Profusa Adds Head of Vascular Surgery Department at AZ Sint Blasius Hospital, Belgium to Growing Customer Base

1. Profusa expands its European customer base through collaboration with AZ Sint Blasius Hospital. 2. Dr. Deloose integrates Profusa’s Lumee system in clinical practices for CLTI treatments. 3. The partnership aims to improve outcomes for patients suffering from critical limb ischemia. 4. Dr. Deloose's expertise in vascular surgery strengthens Profusa's market position. 5. Profusa focuses on innovative technology for continuous biochemical monitoring.

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Why Bullish?

The collaboration showcases increasing market adoption, which may enhance revenue potential. Historical partnerships have often led to increased stock valuations in health tech.

How important is it?

The ongoing collaboration with a renowned surgeon positions Profusa advantageously within the European market.

Why Long Term?

This collaboration is likely to yield sustained growth over time as CLTI treatments progress. Previous collaborations in the health sector have taken 1-3 years to fully impact stock performance.

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Internationally recognized vascular surgeon, Dr. Koen Deloose provides patient access to latest innovative treatments and personalized care BERKELEY, Calif, Sept. 04, 2025 (GLOBE NEWSWIRE) -- Profusa, Inc. (“Profusa” or the “Company”) (Nasdaq: PFSA), a commercial stage digital health company pioneering a next-generation technology platform enabling the continuous monitoring of an individual’s biochemistry, announces continued growth in its customer base in Europe, with a new commercial and clinical collaboration with the Department of Vascular Surgery at AZ Sint Blasius Hospital, Belgium.  Koen R. Deloose, M.D., BSVS, head of the department, is an internationally recognized vascular surgeon specializing in critical limb ischemia (“CLTI”) with over 300 CLTI patients treated annually and will spearhead the collaboration at the key center.   Dr. Deloose also serves in leadership roles at a clinic research organization (“CRO”) and in major European medical conferences. “I personally used the Lumee™ Oxygen measurement to monitor endovascular revascularization procedures in below the knee cases. Profusa’s technology provides a critical real-time tissue oxygen perfusion metric that is essential for our successful treatment of these patients,” said Dr. Deloose. “My case data highlighted the relationships between oxygen dynamics measured at point locations, anatomical target of delivered interventions, and treatment outcome. I’m convinced this technology will offer us more guidance in the treatment and follow-up of a constantly growing CLTI-population.” Dr. Deloose recently opened a modern vascular clinic with a multidisciplinary approach that includes diabetic foot specialists, wound care experts and podiatrists, to provide patient access to the latest treatments and personalized care.  Dr. Deloose is chief medical officer of the CRO Kando Research, focusing on advancing vascular medicine and providing patients with early access to innovative technologies.  He is also founding co-course director and board member of the organizing committee of Paris Vascular Insights and a member of the EVC Maastricht board.  As an active researcher, Dr. Deloose has authored and co-authored more than 200 articles in peer-reviewed medical journals, more than 10 chapters in orthopedic, vascular and endovascular books, and is editorial board member of the Journal of Cardiovascular Surgery and the Journal of Critical Limb Ischemia, Endovascular Section. "We continue to add to our impressive roster of customers and warmly welcome Dr. Deloose to our network.  The combination of Dr. Deloose’s clinical approach and CLTI research programs that advance the campaign against major amputations due to vascular and arterial diseases speaks to Profusa’s mission to make our body's chemistry easily accessible, improving health and wellness,” said Ben Hwang, Ph.D., Profusa’s Chairman and CEO.  “We look forward to contributing to Dr. Deloose’s clinical agenda with our Lumee Oxygen monitoring system and to future collaborations as we progress target indications of our platform technology.”   About Profusa Based in Berkeley, Calif., Profusa is a commercial stage digital health company led by visionary scientific founders, an experienced management team and a world-class board of directors in the development of a new generation of tissue-integrated sensors to detect and continuously transmit actionable, medical-grade data for personal and medical use. With its long-lasting, injectable and affordable biosensors and its intelligent data platform, Profusa aims to provide people with a personalized biochemical signature rooted in data that clinicians can trust and rely on. “LUMEE”, “PROFUSA” and the PROFUSA logo are registered trademarks of Profusa Inc. in the United States, Canada, European Union, China, Japan, South Korea and Australia. For more information, visit https://profusa.com. Special Note Regarding Forward-Looking Statements Certain statements in this press release (this “Press Release”) may be considered “forward-looking statements” within the meaning of the “safe harbor” provisions of the United States Private Securities Litigation Reform Act of 1995. Forward-looking statements generally relate to future events or future financial or operating performance of Profusa or the combined company. In some cases, you can identify forward-looking statements by terminology such as “anticipate,” “believe,” “continue,” “could,” “estimate,” “expect,” “forecast,” “future,” “intend,” “may,” “might,” “plan,” “possible,” “potential,” “predict,” “project,” “propose,” “seek,” “should,” “strive,” “will,” or “would” or the negatives of these terms or variations of them or similar terminology. Such forward-looking statements are subject to risks, uncertainties, and other factors which may be beyond the control of Profusa and could cause actual results to differ materially from those expressed or implied by such forward-looking statements. These forward-looking statements are based upon estimates and assumptions that, while considered reasonable by Profusa and its management are inherently uncertain. Profusa cautions you that these statements are based on a combination of facts and factors currently known and projections of the future, which are inherently uncertain. There are risks and uncertainties described in the definitive proxy/final prospectus relating to the business combination, which has been filed with the SEC, and in other documents filed by Profusa from time to time with the SEC. These filings may identify and address other important risks and uncertainties that could cause actual events and results to differ materially from those contained in the forward-looking statements. Profusa cannot assure you that the forward-looking statements in this communication will prove to be accurate. Contacts Investor and Media Contactsemail:  info@coreir.comphone:  1 (212) 655-0924

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