ProPhase Labs (NASDAQ: PRPH) Enters Non-Binding LOI for Proposed Reverse Merger with Advanced Biological Laboratories
On December 19, 2025, ProPhase Labs, Inc. (NASDAQ: PRPH) announced a significant development in its corporate strategy. The company disclosed that it has signed a non-binding Letter of Intent (LOI) with Advanced Biological Laboratories S.A. (ABL), a European biotechnology and MedTech leader, concerning a proposed reverse merger. This transaction aims to drive near-term value for ProPhase shareholders while ensuring long-term growth prospects for ABL.
Details of the Proposed Transaction
The LOI outlines preliminary discussions but does not bind either party to complete the merger, except for standard confidentiality and expense clauses. The merger is contingent upon:
- Completion of due diligence.
- Negotiation and finalization of definitive agreements.
- Obtaining regulatory approvals.
- Meeting Nasdaq listing requirements.
Initial estimates propose a valuation of ProPhase's legacy business of approximately $30 million. If finalized, ProPhase may enact a special cash dividend of up to $10 million for its shareholders, with further financial specifics expected to evolve prior to completion.
Strategic Rationale and Leadership Insights
Ted Karkus, CEO of ProPhase Labs, expressed enthusiasm about the LOI, stating, “This LOI represents what we believe is one of the most important strategic developments in ProPhase Labs’ history.” He emphasized that this transaction is structured to provide meaningful immediate value to shareholders while aligning ProPhase with ABL’s extensive resources in molecular analysis and healthcare innovation.
Transaction Structure and Ownership
Upon closing the proposed transaction, ABL shareholders would hold approximately 76% of the combined entity. A new U.S. subsidiary would manage ProPhase’s key platforms, including:
- Nebula Genomics.
- BE-Smart Esophageal Cancer Test.
- Selected consumer health businesses.
This subsidiary will operate with ProPhase’s current management team, while ABL enhances the operational capacity through advanced infrastructure and financial prowess.
Benefits for ProPhase Shareholders
The LOI includes provisions to declare a special cash dividend, potentially amounting to $10 million, and carve out the Crown Medical Collections receivables for ProPhase shareholders. With anticipated collections of approximately $50 million net from these receivables, current shareholders are positioned for unique financial benefits independent of the merged entity's performance.
Asset and Liability Considerations
Under the proposed structure, the new operating company will assume only the liabilities explicitly agreed upon in final documentation, including an estimated $5 million of ProPhase's existing debts. All other legacy liabilities will remain with ProPhase Labs.
Next Steps and Conference Call
ProPhase anticipates moving forward with definitive agreements within the next 60 to 90 days. Moreover, a virtual conference call is scheduled for today at 10:00 a.m. ET, where the CEO will elaborate on the transaction's implications for shareholders. Interested parties can register for the call at Renmark Financial Communications.
About Advanced Biological Laboratories S.A.
ABL is a prominent MedTech and biotechnology group based in Europe, providing cutting-edge solutions for molecular diagnostics and clinical research, enhancing patient outcomes through innovative technologies and healthcare practices.
About ProPhase Labs, Inc.
ProPhase Labs, Inc. (NASDAQ: PRPH) operates within diversified diagnostics and genomics, focusing on innovative consumer health and precision medicine solutions, such as Nebula Genomics and the BE-Smart Esophageal Cancer Test.
Disclaimer
This announcement contains forward-looking statements as defined by the Private Securities Litigation Reform Act of 1995. Actual results may differ due to various uncertainties including due diligence and market conditions.