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Rafael Holdings Reports Third Quarter Fiscal 2025 Financial Results

1. Rafael Holdings completed merger with Cyclo Therapeutics on March 25, 2025. 2. The ongoing Phase 3 trial for Niemann-Pick Disease Type C1 is fully enrolled. 3. A $25 million rights offering closed to support clinical advancements. 4. Net loss for Q3 2025 decreased significantly compared to previous year. 5. Upcoming interim analysis results may influence RFL's market perception.

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FAQ

Why Bullish?

The merger with Cyclo Therapeutics and upcoming trial results could drive investor interest. Historically, similar biotech mergers have led to positive stock performance when successful.

How important is it?

New clinical results and fiscal stability enhance investor confidence in RFL's stock. High relevance due to mergers and clinical developments directly impacting RFL.

Why Short Term?

The interim analysis results are imminent and could quickly influence stock performance. Short-term biotech performance is often reactive to trial data announcements.

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Cyclo Therapeutics’ TransportNPC™ Phase 3 clinical trial for Trappsol® Cyclo™ for the treatment of Niemann-Pick Disease Type C1, a rare and fatal genetic disease, is fully enrolled and results from the 48-week interim analysis are expected later this month June 11, 2025 07:00 ET  | Source: Rafael Holdings, Inc. NEWARK, N.J., June 11, 2025 (GLOBE NEWSWIRE) -- Rafael Holdings, Inc. (NYSE: RFL; NYSE American: RFL-WT), today reported its financial results for the third quarter and first nine months of fiscal year 2025 ended April 30, 2025. “We are pleased to have completed our merger with Cyclo Therapeutics and look forward to reporting the topline data from the 48-week interim analysis of the pivotal Phase 3 TransportNPC™ study evaluating Trappsol® Cyclo™ for the treatment of Niemann-Pick Disease Type C1 anticipated later this month,” said Howard Jonas, Chief Executive Officer, Executive Chairman and Chairman of the Board of Rafael Holdings. Mr. Jonas added, “We have enhanced our financial position with the closing of a $25 million rights offering earlier this month which will support advancing this potential new treatment option for patients suffering from this rare genetic disease.” Rafael Holdings, Inc. Third Quarter Fiscal Year 2025 Financial Results As of April 30, 2025, we had cash and cash equivalents of $37.9 million. On June 4, 2025, the Company announced the closing of a $25 million rights offering, which, including the funding of the backstop commitment by the Jonas family, raised net proceeds of $24.9 million after deduction of certain expenses incurred in connection with the offering. For the three months ended April 30, 2025, we recorded a net loss attributable to Rafael Holdings of $4.8 million, or $0.19 per share, versus a net loss of $32.4 million, or $1.36 per share in the year ago period. The year over year decrease in net loss is attributable to non-cash items, primarily unrealized losses of $1.4 million on the Company’s investment in Cyclo equity which we purchased in advance of the potential merger in the current period versus $4.4 million in the year ago period, combined with an in-process R&D expense of $89.9 million related to the acquisition of Cornerstone, partially offset by a $31.3 million recovery of receivables from Cornerstone in the year ago period. Research and development expenses were $3.0 million for the three months ended April 30, 2025, compared to $1.5 million in the year ago period. The year over year increase relates to the inclusion in the current year period of spending at Cyclo Therapeutics following the March 25, 2025 merger and the activity of Cornerstone and Day Three which were consolidated with Rafael Holdings during fiscal 2024. General and administrative expenses were $3.2 million for the three months ended April 30, 2025, compared to $1.9 million in the year ago period. The year over year increase relates to the inclusion of Cyclo Therapeutics following closing of the merger, and the activity of Cornerstone and Day Three, following their consolidation. Rafael Holdings, Inc. First Nine Months Fiscal Year 2025 Financial Results For the nine months ended April 30, 2025, we recorded a net loss attributable to Rafael Holdings of $18.4 million, or $0.73 per share, versus a net loss of $29.9 million, or $1.26 per share in the year ago period. The year over year decrease in net loss is attributable to in-process R&D expense of $89.9 million related to the acquisition of Cornerstone net with a $31.3 million recovery of receivables from Cornerstone in the year ago period and $3.2 million in unrealized gains on the Company’s investment in Cyclo equity. Research and development expenses were $5.3 million for the nine months ended April 30, 2025, compared to $2.6 million in the year ago period. The year over year increase relates to the merger with Cyclo Therapeutics which closed on March 25, 2025, and the activity of Cornerstone and Day Three, which were consolidated with Rafael Holdings during fiscal 2024. For the nine months ended April 30, 2025, general and administrative expenses were $8.3 million compared to $6.5 million in the same period in the prior year. The year over year increase relates to the merger with Cyclo Therapeutics which closed on March 25, 2025, and the activity of Cornerstone and Day Three, which were consolidated with Rafael Holdings during fiscal 2024. About Rafael Holdings, Inc. Rafael Holdings, Inc. holds interests in clinical and early-stage pharmaceutical and certain other companies, including our wholly owned subsidiary, Cyclo Therapeutics, LLC, a clinical stage biotechnology company dedicated to developing Rafael’s lead clinical candidate, Trappsol® Cyclo™, which is being evaluated in clinical trials for the potential treatment of Niemann-Pick Disease Type C1 (“NPC1”), a rare, fatal, and progressive genetic disorder. Rafael also holds majority equity interests in LipoMedix Pharmaceuticals Ltd., a clinical stage pharmaceutical company, Cornerstone Pharmaceuticals, Inc., formerly known as Rafael Pharmaceuticals Inc., a cancer metabolism-based therapeutics company, Rafael Medical Devices, LLC, an orthopedic-focused medical device company developing instruments to advance minimally invasive surgeries, and Day Three Labs, Inc., a company which empowers third-party manufacturers to reimagine their existing cannabis offerings.  Forward Looking Statements This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this press release that do not relate to matters of historical fact should be considered forward-looking statements, including without limitation statements regarding our expectations surrounding the potential, safety, efficacy, and regulatory and clinical progress of our product candidates; plans regarding the further evaluation of clinical data; and the potential of our pipeline, including our internal cancer metabolism research programs. These statements are neither promises nor guarantees, but involve known and unknown risks, uncertainties and other important factors that may cause our actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements, including, but not limited to, those disclosed under the caption “Risk Factors” in our Annual Report on Form 10-K for the year ended July 31, 2024, and our other filings with the SEC. These factors could cause actual results to differ materially from those indicated by the forward-looking statements made in this press release. Any such forward-looking statements represent management’s estimates as of the date of this press release. While we may elect to update such forward-looking statements at some point in the future, we disclaim any obligation to do so, even if subsequent events cause our views to change. Contact:Barbara RyanBarbara.ryan@rafaelholdings.com(203) 274-2825       RAFAEL HOLDINGS, INC.     CONSOLIDATED BALANCE SHEETS      (in thousands, except share and per share data)             April 30, 2025 July 31, 2024     (audited) ASSETS           CURRENT ASSETS     Cash and cash equivalents $37,936  $2,675  Available-for-sale securities  —   63,265  Interest receivable  —   515  Prepaid clinical trial costs  2,968   —  Convertible note receivables, due from Cyclo  —   5,191  Accounts receivable, net of allowance for credit losses of $245 at April 30, 2025 and July 31, 2024  414   426  Inventory  288   —  Prepaid expenses and other current assets  837   430  Total current assets  42,443   72,502        Property and equipment, net  1,614   2,120  Non-current prepaid clinical trial costs  1,399   —  Investments – Cyclo  —   12,010  Investments - Hedge Funds  —   2,547  Convertible note receivable classified as available-for-sale  1,719   1,146  Goodwill  28,278   3,050  Intangible assets, net  1,027   1,847  In-process research and development  31,575   1,575  Other assets  41   35  TOTAL ASSETS $108,096  $96,832        LIABILITIES AND EQUITY     CURRENT LIABILITIES     Accounts payable $7,793  $2,556  Accrued expenses  1,866   1,798  Convertible notes payable  614   614  Other current liabilities  93   113  Due to related parties  664   733  Installment note payable  —   1,700  Total current liabilities  11,030   7,514        Accrued expenses, noncurrent  3,445   2,982  Convertible notes payable, noncurrent  76   73  Other liabilities  25   5  Deferred income tax liability  9,002   —  TOTAL LIABILITIES  23,578   10,574        COMMITMENTS AND CONTINGENCIES           EQUITY     Class A common stock, $0.01 par value; 35,000,000 shares authorized, 787,163 shares issued and outstanding as of April 30, 2025 and July 31, 2024  8   8  Class B common stock, $0.01 par value; 200,000,000 shares authorized, 31,240,188 issued and outstanding (excluding treasury shares of 101,487) as of April 30, 2025, and 24,142,535 issued and 23,819,948 outstanding (excluding treasury shares of 101,487) as of July 31, 2024  312   238  Additional paid-in capital  296,648   280,048  Accumulated deficit  (220,169)  (201,743) Treasury stock, at cost; 101,487 Class B shares as of October 31, 2024 and July 31, 2024  (168)  (168) Accumulated other comprehensive income related to unrealized income on available-for-sale securities  219   111  Accumulated other comprehensive income related to foreign currency translation adjustment  3,728   3,691  Total equity attributable to Rafael Holdings, Inc.  80,578   82,185  Noncontrolling interests  3,940   4,073  TOTAL EQUITY  84,518   86,258        TOTAL LIABILITIES AND EQUITY $108,096  $96,832              RAFAEL HOLDINGS, INC.    CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS     (unaudited, in thousands, except share and per share data)                       Three Months Ended April 30,  Nine Months Ended April 30,    2025   2024   2025   2024  Revenues$362  $336  $567  $472           Cost of Infusion Technology revenue 31   85   106   85  Cost of product revenue 9   —   9   —  SG&A Expenses 3,170   1,923   8,284   6,524  R&D Expenses 3,003   1,526   5,276   2,627  In-process R&D expense —   89,861   —   89,861  Depreciation and amortization 62   102   238   157  Loss on impairment of goodwill —   —   3,050   —  Operating Loss (5,913)  (93,161)  (16,396)  (98,782)          Interest income 472   502   1,529   1,777  Loss on initial investment in Day Three upon acquisition —   —   —   (1,633) Realized gain on available-for-sale securities —   945   178   1,521  Realized loss on investment in equity securities —   —   —   (46) Realized gain on investment - Cyclo —   —   —   424  Unrealized (loss) gain on investments - Cyclo (1,393)  (4,395)  (5,144)  3,199  Unrealized gain (loss) on convertible notes receivable, due from Cyclo 383   —   (719)  —  Unrealized loss on investments - Hedge Funds —   (3)  —   (118) Recovery of receivables from Cornerstone —   31,305   —   31,305  Interest expense (165)  (85)  (490)  (85) Other income, net 154   —   74   118  Loss before Incomes Taxes (6,462)  (64,892)  (20,968)  (62,320) Benefit from income taxes 2,411   2,599   2,379   2,593  Equity in loss of Day Three —   —   —   (422) Consolidated net loss (4,051)  (62,293)  (18,589)  (60,149) Net income (loss) attributable to noncontrolling interests 728   (29,942)  (163)  (30,207) Net loss attributable to Rafael Holdings, Inc.$(4,779) $(32,351) $(18,426) $(29,942)                   Loss per share        Basic and diluted (0.19)  (1.36)  (0.73)  (1.26) Loss per basic common share$(0.19) $(1.36) $(0.73) $(1.26)          Weighted average shares in calculation 25,238,501   23,777,493   23,131,655   23,687,781           

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