StockNews.AI
BNTX
StockNews.AI
152 days

Refractory Metastatic Melanoma Pipeline Report 2025, with Focus on BioNTech SE, Y-mAbs and Therapeutics Seagen

1. BNT111 is in Phase II for Refractory Metastatic Melanoma. 2. Over 90% of melanoma patients express targeted antigens. 3. BNT111 has FDA Fast Track and Orphan Drug designations. 4. BioNTech collaborates on therapies for metastatic melanoma. 5. 4+ companies are developing treatments for melanoma.

6m saved
Insight
Article

FAQ

Why Bullish?

The progression of BNT111 and FDA designations may enhance investor confidence and stock value.

How important is it?

BNT111's advanced trial status and FDA designations create significant market potential.

Why Long Term?

As BNT111 moves forward, successful outcomes could significantly boost BNTX's market position over time.

Related Companies

NOVNMRNASEGN
Dublin, March 20, 2025 (GLOBE NEWSWIRE) -- The "Refractory Metastatic Melanoma - Pipeline Insight, 2025" clinical trials has been added to ResearchAndMarkets.com's offering.The report provides comprehensive insights about 4+ companies and 4+ pipeline drugs in Refractory Metastatic Melanoma pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.Report HighlightsThe companies and academics are working to assess challenges and seek opportunities that could influence Refractory Metastatic Melanoma R&D. The therapies under development are focused on novel approaches to treat/improve Refractory Metastatic Melanoma.Refractory Metastatic Melanoma Emerging Drugs ChaptersThis segment of the Refractory Metastatic Melanoma report encloses its detailed analysis of various drugs in different stages of clinical development, including Phase III, II, I, Preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.Refractory Metastatic Melanoma Emerging Drugs BNT111: BioNTech SE BNT111 is an mRNA cancer vaccine candidate encoding a fixed set of four melanoma-associated antigens aiming to trigger a strong and precise immune response in patients with anti-PD-(L) 1 refractory/relapsed, unresectable Stage III or IV melanoma. BNT111 is an mRNA-based off-the-shelf cancer immunotherapy candidate for intravenous administration encoding a fixed set of four non-mutated melanoma-associated antigens (NY-ESO-1, MAGE-A3, tyrosinase, and TPTE) delivered as uridine mRNA-lipoplex formulation. Over 90% of patients with cutaneous melanomas express at least one of these antigens. The BNT111 program has also received Fast Track designation and Orphan Drug designation from the U.S. Food and Drug Administration. Currently, the drug is in Phase II stage of its development for the treatment of Refractory Metastatic Melanoma. GD2-SADA: Y-mAbs Therapeutics The GD2-SADA construct is created using SADA technology, that utilizes a pre-targeted payload delivery method where antibody constructs assemble in tetramers and bind to the tumor target. Unbound constructs predictably disassemble into smaller antibody fragments and are excreted through the kidneys within hours after administration. In a second infusion, a radioactive payload binds to the antibody constructs attached to the tumor target in order to radiate the tumor. This provides the possibility of targeting tumors with precision while minimizing radiation of normal tissues. The SADA technology platform can deliver a variety of payloads and could potentially be developed against multiple tumor targets, as well as for theragnostic purposes. Currently, the drug is in Phase I stage of its development for the treatment of Refractory Metastatic Melanoma. Refractory Metastatic Melanoma: Therapeutic AssessmentThis segment of the report provides insights about the different Refractory Metastatic Melanoma drugs segregated based on following parameters that define the scope of the report, such as:Major Players in Refractory Metastatic Melanoma There are approx. 4+ key companies which are developing the therapies for Refractory Metastatic Melanoma. The companies which have their Refractory Metastatic Melanoma drug candidates in the most advanced stage, i.e. Phase II include, BioNTech SE. Key Players BioNTech SEY-mAbs TherapeuticsSeagen Inc. Key Products BNT111GD2-SADASEA-CD40 For more information about this clinical trials report visit https://www.researchandmarkets.com/r/9xsvmj About ResearchAndMarkets.comResearchAndMarkets.com is the world's leading source for international market research reports and market data. We provide you with the latest data on international and regional markets, key industries, the top companies, new products and the latest trends.

Related News