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Telix and Varian Announce Strategic Theranostics-EBRT Clinical Collaboration

1. Telix partners with Varian for novel clinical applications. 2. Collaboration focuses on integrating theranostics with EBRT. 3. The partnership enhances personalized treatment strategies for prostate cancer. 4. Molecular imaging and radiopharmaceuticals improve patient selection in oncology. 5. Future co-development opportunities are planned beyond initial focus on PSMA imaging.

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Why Bullish?

Strategic collaborations often drive stock value due to expanded market potential and technical advancements. Historical cases include acquisitions that led to increased share prices, such as Amgen's acquisition of Onyx Pharmaceuticals, which significantly enhanced its oncology portfolio.

How important is it?

The collaboration positions Telix uniquely in the oncology market, enhancing its growth potential. The agreement also supports exploration of multiple product candidates, increasing the company's future revenue streams.

Why Long Term?

As clinical applications take time to develop and gain regulatory approval, the long-term outlook remains promising. Similar partnerships in biotech have historically led to major breakthroughs but require time for solid results.

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Telix Pharmaceuticals and Varian Unite for Advanced Cancer Treatment Collaboration

MELBOURNE, Australia and PALO ALTO, Calif., Dec. 10, 2025 (GLOBE NEWSWIRE) — Telix Pharmaceuticals Limited (ASX: TLX, NASDAQ: TLX) has announced a strategic clinical collaboration with Varian, a Siemens Healthineers company, to explore innovative applications that combine Telix’s theranostic products with external beam radiation therapy (EBRT). This collaboration aims to enhance treatment for solid malignant tumors, a significant milestone in oncological care.

Objective of the Collaboration

The partnership between Telix and Varian focuses on integrating advanced imaging and theranostics into the radiation therapy workflow. By collaborating, they aim to improve precision in patient selection and treatment personalization for radiation oncologists, ultimately enhancing patient outcomes.

Initial Investigations and Clinical Applications

The initial investigational focus will center on PSMA-PET imaging for prostate cancer radiotherapy patients. Through this collaboration, Telix plans to leverage its theranostic products, Gozellix® and Illuccix®, in conjunction with Varian’s cutting-edge EBRT technologies. Key elements of their framework include:

  • Utilizing Gozellix® for patient selection in EBRT.
  • Developing personalized treatment plans within Varian’s Ethos adaptive radiotherapy.
  • Monitoring treatment responses via advanced imaging techniques.

This strategic alliance supports both clinician-sponsored and investigator-led studies, setting the stage for extensive clinical trials and innovative treatment methodologies.

Future Potential of the Collaboration

While the immediate focus is on prostate cancer imaging, the collaboration serves as a foundation for broader co-development opportunities. This includes various PET imaging candidates from Telix’s pipeline, such as TLX250-CDx (Zircaix®) and TLX101-CDx (Pixclara®), as well as future radiopharmaceutical therapies. The combined expertise in radiopharmaceuticals and EBRT positions radiation oncologists to lead both definitive and palliative care strategies.

Statements from Leadership

Dr. Arthur Kaindl, Head of Varian, remarked, “Collaborating with Telix opens a powerful pathway to embed precision imaging and theranostics into the radiation therapy workflow, advancing how we personalize and optimize treatment decisions.” In parallel, Dr. Christian Behrenbruch, Group CEO and Managing Director of Telix, stated, “This partnership represents a transformative opportunity to bring precision imaging into the heart of radiation oncology, potentially improving patient outcomes through innovative cancer care solutions.”

Important Safety Information

As with any therapeutic approach, it is critical to understand the risks associated with the use of Gozellix and Illuccix. Key safety considerations include:

  • Possible misinterpretation of PET images, necessitating clinical correlation.
  • Increased long-term radiation exposure risks associated with gallium Ga-68 gozetotide.
  • Potential allergic reactions to components in the therapeutic agents.

Healthcare providers should ensure appropriate handling and patient preparation to mitigate risks.

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