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Verastem's PDAC data at RP2D show strong early signals; catalysts loom

Jun 17, 2026, 7:33 AM EDT2 sourcesAI-analyzed
Why it may matterVerify against the original reporting

Positive early efficacy signals and a potential collaboration catalyst could lift sentiment; however, small sample size and lack of regulatory approval pause conviction.

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Verastem Oncology reported positive updated safety and efficacy from the RAMP 205 RP2D cohort in first-line metastatic pancreatic ductal adenocarcinoma (PDAC). The data show 6-month OS of 86%, PFS 68%, and an ORR of 52% (15/29), with 83% tumor shrinkage at RP2D. If OS data mature and partnerships form, near-term catalysts could boost valuations.

  • RAMP 205 RP2D cohort includes 29 patients in first-line PDAC.
  • 6-month OS 86%; PFS 68%; ORR 52% (15/29).
  • 90% metastatic at diagnosis; 83% tumor shrinkage at RP2D.
  • Potential collaborations; data may drive future partnerships and further trials.

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