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JNJ's TREMFYA Shows Durable Crohn's Remission in 3-Year GALAXI Data

Oct 12, 2026, 4:13 PM EDT2 sourcesAI-analyzed
Why it may matterVerify against the original reporting

Strong 3-year efficacy signals may bolster TREMFYA's value proposition in Crohn's, potentially supporting a positive stock reaction; however, the data are prescriptive results, not an FDA approval, so the move may be modest and sentiment-driven until payer access or labeled indications change.

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Johnson & Johnson unveiled three-year GALAXI 2/3 results for TREMFYA in Crohn's disease, demonstrating durable clinical and endoscopic remission through Week 144. High remission rates and continued treatment suggest meaningful long-term disease control, potentially strengthening TREMFYA's position in IBD and supporting near-term investor sentiment around JNJ's immunology portfolio.

  • Three-year GALAXI 2/3 data show TREMFYA durability in Crohn's. Week 144 data across regimens.
  • Clinical remission at Week 144: 94% (q8w) and 91% (q4w).
  • 90-day corticosteroid-free remission: 88% across both regimens.
  • Endoscopic remission: 52% (q8w) and 61% (q4w); 74% remained on TREMFYA through three years.
  • Data presented at ACG 2026; TREMFYA dual-acting IL-23/CD64 mechanism highlighted.

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