HC Wainwright raises CRIS's price target to $43 on TakeAim CLL progress and potential CLL, PCNSL, and NHL opportunities. Key timelines shift with PCNSL to 2029 and AML/MDS to 2032; enrollment targeted by 2027 and potential accelerated approvals, supported by improving DoR in BTKi-experienced patients. The readouts could be near-term catalysts for upside if data meet expectations.
Curis announced updated TakeAim PCNSL results and stronger TakeAim CLL enrollment, with year-end data guidance raised. BTKi-naïve PCNSL patients show 100% ORR; BTKi-experienced 33% ORR, signaling potential regulatory progress. While data quality supports a near-term regulatory pathway, the company’s cash runway remains a funding risk.