William Blair initiated coverage on Enliven Therapeutics with an Outperform rating, highlighting ELVN-001's potential to reshape CML therapy. The catalyst is the coverage stance and potential progress updates, though no trial data were disclosed. If ELVN-001 delivers positive data or milestones, ELVN could see near-term re-rating.
ELVN shares surge 50.42%, trading at $23.27. Phase 1b ENABLE trial shows strong efficacy for ELVN-001 in CML. 38% MMR and 16% DMR rates in 80 mg cohort; 53% MMR in 60 mg cohort. No new safety signals observed; favorable safety profile maintained. Phase 3 ENABLE-2 trial set to begin in second half of 2026.