New MIRACLE trial data show Annamycin arms achieved higher CRc after one cycle (50% and 57%) versus 29% control in relapsed/refractory AML. The Independent Data Monitoring Committee recommended keeping both doses and continuing the trial, with significance expected only at the final analysis under the O’Brien-Fleming design. Moleculin Biotech stock dropped about 26% on the news.
Moleculin Biotech's preliminary results from the MIRACLE study reveal promising remission rates exceeding 40% for Annamycin combined with cytarabine, compared to historical rates. Despite this, the stock's recent decline of over 32% year-to-date may present a buying opportunity for investors anticipating further positive updates as enrollment continues through 2026.