Stoke Therapeutics reports EMPEROR Phase 3 enrollment completed (162 patients) with readout anticipated in Q3 2027 and a pre-NDA meeting planned for H2 2026. The company also advances STK-002 for ADOA, with initial safety/efficacy data expected in H1 2027. With about $420 million in cash, Stoke aims for U.S. commercialization by early 2028, underpinning a multi-year regulatory path.
Stoke CEO Dr. Edward Kaye resigns, interim CEO Ian Smith appointed. Q4 revenue reached $22.61 million, exceeding analyst consensus greatly. Company reported a smaller-than-expected loss of $0.18 per share. Stoke has $246.7 million in cash, funding operations through mid-2028. Shares fell nearly 3% but up over 40% in the last year.