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Filgotinib Shows Positive Topline Results Across Full Spectrum of Axial Spondyloarthritis in OLINGUITO Phase 3 Study

1. Alfasigma's filgotinib shows positive Phase 3 results for treating axSpA. 2. This may influence competing treatments in the market, affecting SPPI.

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FAQ

Why Neutral?

The positive results for filgotinib enhance Alfasigma's market position. Historically, similar announcements have led to temporary volatility in related stocks, but direct impact on SPPI remains uncertain.

How important is it?

The results of the trial could impact SPPI indirectly through competitive pressures. Positive outcomes for a competitor can reshape market dynamics, encouraging a reassessment of SPPI's strategies and product pipeline.

Why Short Term?

Immediate market reaction may occur, but long-term effects depend on further clinical developments and market acceptance of filgotinib.

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BOLOGNA, Italy--(BUSINESS WIRE)--Alfasigma S.p.A today announced positive topline results from the OLINGUITO Phase 3 clinical trial (NCT05785611; Eudra CT 2022-501354-10-01),i evaluating filgotinib (marketed as Jyseleca® in approved indications) to treat adult patients with active axial spondyloarthritis (axSpA). Filgotinib, an oral, once-daily JAK1 preferential inhibitor, met the primary endpoint in the OLINGUITO Phase 3 clinical trial in active axSpA. Efficacy was demonstrated across the full.

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