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Milestone Scientific Appoints Dr. Dawood Sayed to Board of Directors to Advance Commercial and Clinical Strategy in Pain Management

1. Dr. Dawood Sayed joins Milestone Scientific's Board, enhancing clinical expertise. 2. His experience will support CompuFlo® adoption in pain management markets. 3. CompuFlo® technology offers safer and more reliable epidural procedures. 4. Medicare's recent payment rate could enhance traction and investor interest. 5. Company aims to accelerate market growth and reduce reliance on opioids.

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Why Bullish?

Dr. Sayed's appointment is likely to boost CompuFlo®'s adoption and market credibility, similar to historical impacts seen when companies strengthened their boards with industry experts. For instance, firms in tech or biotech often see stock price increases following such strategic hires due to perceived advancements in product efficacy and market readiness.

How important is it?

The appointment of a respected figure in pain management could elevate stakeholder confidence and enhance clinical trials, thus driving market interest in MLSS. Given that market conditions often shift swiftly in response to leadership changes, this development carries significance.

Why Long Term?

The full effect of Dr. Sayed's influence on Milestone's growth trajectory may take time, similar to other instances where new board members have taken time to implement changes. Successful adoption of new technologies in the medical space often spans years of clinical validation and payer negotiations.

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Appointment strengthens Board expertise as Milestone Scientific drives commercial expansion and payer adoption of CompuFlo® in interventional pain management September 22, 2025 09:15 ET  | Source: Milestone Scientific, Inc. ROSELAND, N.J., Sept. 22, 2025 (GLOBE NEWSWIRE) -- Milestone Scientific Inc. (NYSE: MLSS), a leading developer of computerized drug delivery instruments that provide painless and precise injections, today announced the appointment of Dawood Sayed, M.D., a nationally recognized leader in interventional pain medicine, to its Board of Directors, effective immediately. Dr. Sayed is a Professor of Anesthesiology and Pain Medicine at the University of Kansas Medical Center and currently serves as Division Chief of Pain Medicine, Director of Interventional Spine Services, and Director of the Center for Neuromodulation. With a robust clinical, academic, and policy background, he brings over a decade of leadership in pioneering minimally invasive pain therapies, neuromodulation, and health system innovation. Dr. Sayed also serves as Vice Chairman and Co-Founder of the American Society of Pain and Neuroscience (ASPN), where he works closely with key stakeholders, including commercial payers, regulators, and medical device manufacturers to advance access to innovative pain relief technologies. His leadership has earned him multiple honors, including the 2025 Presidential Award from the North American Neuromodulation Society (NANS). “We are honored to welcome Dr. Sayed to the Milestone Scientific Board,” stated Neal Goldman, Chairman of Milestone Scientific. “His deep expertise in pain medicine and strong relationships across the clinical and payer communities will be instrumental as we expand adoption of CompuFlo® across pain management and spine intervention markets. With this appointment, we complete our strategic initiative to bring prominent medical voices to the Board, ensuring that Milestone remains aligned with the evolving needs of patients, physicians, and payers.” Milestone Scientific’s CompuFlo® Epidural System is a groundbreaking platform technology that precisely identifies the epidural space with real-time pressure feedback, offering a safer and more reliable alternative to traditional loss-of-resistance techniques. The technology has been increasingly validated by clinical leaders and was recently assigned a Medicare Part B payment rate under CPT® code 0777T in several jurisdictions. Early activity from commercial insurers also indicates growing interest in supporting technologies that reduce procedural risk and improve outcomes. “Dr. Sayed’s appointment is a significant step forward in our commitment to build a clinically informed, market-driven organization,” commented Eric Hines, Chief Executive Officer of Milestone Scientific. “As we move into the next phase of commercial growth, his knowledge of health system adoption, clinical training, and reimbursement strategy will help accelerate our penetration into the interventional pain management space.” “I am excited to join Milestone Scientific’s Board at a time when innovation in interventional pain care is critical to improving patient outcomes and reducing opioid reliance,” said Dr. Sayed. “CompuFlo® is a truly disruptive technology that addresses a long-standing challenge in spinal procedures. I look forward to working with the team to drive greater clinical adoption and improve procedural safety.” Dr. Sayed has authored over 100 peer-reviewed publications, contributed to national guidelines in pain medicine, and currently leads multiple clinical trials evaluating neuromodulation and spinal therapies. He also serves as a medical advisor to several leading medtech innovators and participates on national AMA CPT® and NANS advocacy committees. About Milestone Scientific Inc.Milestone Scientific Inc. (MLSS) is a technology-focused medical research and development company that patents, designs, and develops innovative injection technologies and instruments for medical and dental applications. Milestone Scientific’s computer-controlled systems are designed to make injections precise, efficient, and increase the overall patient comfort and safety. The Company leverages its proprietary DPS Dynamic Pressure Sensing Technology® platform to advance the development of next-generation devices, regulating flow rate and monitoring pressure from the tip of the needle, through platform extensions of subcutaneous drug delivery, including local anesthetics. To learn more, view the MLSS brand video or visit milestonescientific.com. Safe Harbor StatementThis press release contains forward-looking statements regarding the timing and financial impact of Milestone's ability to implement its business plan, expected revenues, timing of regulatory approvals and future success. These statements involve a number of risks and uncertainties and are based on assumptions involving judgments with respect to future economic, competitive and market conditions, future business decisions and regulatory developments, all of which are difficult or impossible to predict accurately and many of which are beyond Milestone's control. Some of the important factors that could cause actual results to differ materially from those indicated by the forward-looking statements are general economic conditions, failure to achieve expected revenue growth, changes in our operating expenses, adverse patent rulings, FDA or legal developments, competitive pressures, changes in customer and market requirements and standards, and the risk factors detailed from time to time in Milestone's periodic filings with the Securities and Exchange Commission, including without limitation, Milestone's Annual Report for the year ended December 31, 2024. The forward-looking statements in this press release are based upon management's reasonable belief as of the date hereof. Milestone undertakes no obligation to revise or update publicly any forward-looking statements for any reason. Contact:         Crescendo Communications, LLCEmail: mlss@crescendo-ir.comTel: 212-671-1020

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