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MIRA Pharmaceuticals' Second Ketamir-2 Manuscript Accepted for Peer-Reviewed Publication Demonstrating Superior Efficacy in Preclinical Neuropathic Pain Models Versus Ketamine, Gabapentin, or Pregabalin

1. MIRA's Ketamir-2 shows superior pain relief in rodent models. 2. Advancement to Phase 2a trials expected by end of 2025.

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Why Bullish?

The promising results in preclinical trials may positively influence investor confidence and stock valuation. Historical data shows similar trajectories for companies advancing to later trial phases.

How important is it?

The article's focus on drug efficacy and future clinical trials indicates MIRA’s potential growth, directly influencing market perception.

Why Long Term?

Positive drug development outcomes typically have sustained stock impacts as they progress through clinical stages. For example, companies like Neurocrine and Janssen saw significant stock appreciation following milestone achievements.

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Manuscript accepted for publication in Frontiers in Pharmacology, "Oral Administration of Ketamir-2, a Novel Ketamine Analog, Attenuates Neuropathic Pain in Rodent Models via Selective NMDA Antagonism" details Ketamir-2's superior performance in two validated neuropathic pain models and supports advancement to Phase 2a clinical trials by year-end 2025. MIAMI, FL / ACCESS Newswire / August 12, 2025 / MIRA Pharmaceuticals, Inc. (NASDAQ:MIRA) ("MIRA" or the "Company"), a clinical-stage pharmaceutical company developing novel oral therapeutics for neurologic, neuropsychiatric, and metabolic disorders, today announced the acceptance of a second peer-reviewed manuscript describing its lead oral drug candidate, Ketamir-2, in Frontiers in Pharmacology.

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