StockNews.AI
TECH
StockNews.AI
97 days

ScaleReady awards multiple G-Rex® Grants to leading investigators at the University of Southern California (USC) and the Children's Hospital of Los Angeles (CHLA)

1. ScaleReady awarded $1,025,000 in G-Rex Grants for cell therapy research. 2. Novel CAR-T manufacturing platforms are being funded to enhance clinical applications. 3. The G-Rex system is favored for efficient CAR-T cell manufacturing processes. 4. Bio-Techne’s products support high throughput in CGT with G-Rex technology. 5. G-Rex Grant Program has extended millions for future grant applications.

9m saved
Insight
Article

FAQ

Why Bullish?

The investment in innovative cell therapies and manufacturing could lead to increased market credibility and revenue for BIO-TECHNE. Historical instances, such as Gilead's acquisition of Kite Pharma, highlight how investments in cell therapy can significantly enhance a company's stock value.

How important is it?

With substantial funding, the advances in gene modification technologies and successful trials are likely to positively affect biotech stocks, especially TECH, as they cultivate innovations in the CGT space.

Why Long Term?

The grants will support research and development over years, likely leading to clinical successes and new products in extended time frames, similar to prior successful cell therapy rollouts.

Related Companies

GILDKITECARACRSPEDIT
, /PRNewswire/ -- ScaleReady, in collaboration with Wilson Wolf Manufacturing, Bio-Techne Corporation (NASDAQ: TECH) and CellReady announced today three G-Rex Grants that have been awarded to faculty members at the University of Southern California (USC) and the Children's Hospital of Los Angeles (CHLA). The funding totaling $1,025,000 will support the translation of various cell and gene therapy initiatives into the clinic. Dr. Mohamed Abou-el-Enein, Executive Director of the USC/CHLA Cell Therapy Program and Founding Director of the cGMP Facility, received a $300,000 G-Rex Grant to further support the development of a novel non-viral manufacturing platform for CAR-T cell therapies. Initially funded by the INFR5 Grant from the California Institute of Regenerative Medicine (CIRM), this additional support will help accelerate and enhance the platform's progress. "After extensive evaluation, we've identified the G-Rex system as the platform of choice for establishing an efficient, scalable, and cost-effective CAR-T manufacturing process that supports both my lab and our clients within the GMP facility. The system enables high-yield cell expansion, robust scale-up, and impressive consistency within a compact footprint. By integrating this platform, we are advancing our mission as a center of excellence in CAR-T manufacturing and delivering practical solutions for teams bringing cell therapies to patients," said Mohamed Abou-el-Enein M.D., Ph.D. Dr. Saul Priceman, Founding Director of the Keck School of Medicine of USC/ USC Norris Comprehensive Cancer Center for Cancer Cellular Immunotherapy Research (CCCIR), received a $275,000 G-Rex Grant for the development of a G-Rex based CAR-T cell process to advance a novel clinically-active CAR-T cell therapy into a Phase 1/2 clinical trial for the treatment of metastatic solid cancers. The laboratory is also investigating viral and non-viral engineering strategies that will be adapted using the G-Rex platform, which will address current cell manufacturing bottlenecks and help expand preclinical and clinical research efforts. "While our clinical experiences to date have used more conventional cell manufacturing platforms, we are excited about translating our new cellular immunotherapies using the G-Rex production system across the USC and CHLA campuses," said Saul Priceman, Ph.D.  Dr. Shahab Asgharzadeh, Director of the Neuroblastoma Basic and Translational Program at CHLA, received a $250,000 G-Rex Grant to support late-stage preclinical development of a novel Chimeric TGFB Signaling Receptor (CTSR) Enabled Anti-B7H3 CAR-T cell therapy in children and Adolescent and Young Adults (AYA) with Recurrent Solid Tumors.  This program is supported by an existing CIRM CLIN1 Grant. Dr. Preet Chaudhary, Professor of Medicine and Chief of the Nohl Division of Hematology and Center for Blood Diseases in the Department of Medicine, received a $200,000 G-Rex Grant  for the process development and IND submission of a novel Synthetic Immune Receptor (SIR) engineered T cell therapy for the treatment of solid tumors.  This program is supported by a CIRM TRAN1 Grant. "USC and CHLA have assembled a world-class team of innovators in the cell therapy field with the intent of making significant contributions to the cell and gene-modified cell therapy (CGT) field. We are impressed by the thoroughness of their CGT manufacturing selection process and having G-Rex selected as the platform to support their current and future clinical plans is an honor," said John Wilson, CEO of Wilson Wolf and co-inventor of G-Rex. ScaleReady's G-Rex Grant Program is advancing the state of CGT development and manufacturing by awarding individual Grant Awards worth up to $300,000.  With nearly 200 grant awards already made and over 50 new applications in queue, the G-Rex Grant Program has been extended with millions of dollars in additional funding. G-Rex Grant Recipients also gain access to exclusive support from ScaleReady's growing consortium of G-Rex Grant Partners who bring best-in-class tools and technologies as well as unparalleled knowledge and expertise in the areas of cGMP manufacturing, quality and regulatory affairs, CGT business operations, and more. For more information about the G-Rex® Grant Program, please contact [email protected]. About ScaleReadyScaleReady provides the field of cell and gene-modified cell therapy (CGT) with a G-Rex centric manufacturing platform that enables the world's most practical, flexible, scalable, and affordable CGT drug product development and manufacturing. The G-Rex manufacturing platform is currently used by a rapidly growing list of over 800 organizations and is producing drug products for approximately 50% of CGT clinical trials as well as 5 commercially approved CGT drugs. CGT entities relying on the breadth and scope of ScaleReady's expertise can expect to save years of time and millions of dollars on the path to CGT commercialization. For more information about the ScaleReady G-Rex® Grant Program, please contact [email protected]. About Wilson Wolf ManufacturingWilson Wolf (www.wilsonwolf.com) is dedicated to simplifying cell and gene-modified cell (CGT) therapy research, process development, and manufacturing.  This is being accomplished through its scalable G-Rex technology, which is used throughout the world in CGT applications ranging from basic research to commercial drug production. Wilson Wolf's mission is to create hope for cancer patients, one G-Rex® device at a time. About Bio-Techne CorporationBio-Techne Corporation (NASDAQ: TECH) is a global life sciences company providing innovative tools and bioactive reagents for the research and clinical diagnostic communities. Bio-Techne, in partnership with Wilson Wolf, is creating products such as media and cytokines that are specifically tailored to G-Rex® Bioreactors, including right-sized reagent quantities in containers that are tailored to high throughput closed-system manufacturing. For more information on Bio-Techne and its brands, please visit https://www.bio-techne.com or follow the Company on social media at: Facebook, LinkedIn, Twitter or YouTube. Contact: David Clair, Vice President, Investor Relations & Corporate Development[email protected]612-656-4416  About CellReady LLCCellReady is the world's first and only G-Rex centric contract development and manufacturing organization (CDMO) specializing in G-Rex based cell and gene-modified cell therapy development and manufacturing. The company offers a wide range of services to support the development and commercialization of these therapies. CellReady's mission is to create hope for cancer patients, one G-Rex® process at a time. SOURCE Bio-Techne Corporation WANT YOUR COMPANY'S NEWS FEATURED ON PRNEWSWIRE.COM? 440k+ Newsrooms & Influencers 9k+ Digital Media Outlets 270k+ Journalists Opted In

Related News