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The collaboration expands GMAB's pipeline into KRAS-mutant disease with potential milestone economics; although terms aren’t disclosed, such partnerships often drive reevaluation of pipeline value, creating a positive short-term price impulse.
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Genmab A/S and Incyte announced a Phase 1/2 trial evaluating petosemtamab, in combination with INCB161734 and standard chemotherapy, for first-line KRAS G12D-mutated metastatic colorectal cancer. The collaboration expands Genmab's EGFR/LGR5 bispecific program into KRAS-mutant disease, potentially creating a new growth pathway if early signals are favorable and milestones are reached.
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