Genmab's Phase 3 EPCORE DLBCL-1 trial results showed no significant overall survival benefit for epcoritamab against standard chemotherapy, raising concerns regarding its accelerated approval for DLBCL. Despite this, improvements in progression-free survival and other metrics are noted, and analysts still hold a cautiously optimistic view on future trials and potential for market growth.
Genmab discontinues acasunlimab development, focusing on late-stage assets. Analysts previously expected peak sales of $300 million for acasunlimab. Genmab maintains its 2025 financial guidance despite discontinuation. FDA approval received for epcoritamab, enhancing Genmab's position. Potential $8 billion peak sales for three lead assets remains intact.
Genmab is acquiring Merus for $8 billion, focusing on petosemtamab. The acquisition will enhance Genmab’s pipeline in oncology and revenue growth. Petosemtamab expected to generate over $1 billion in annual sales by 2029. Transaction will close in early 2026, funded through cash and debt. Analysts view the acquisition positively, reinforcing long-term growth potential.