Kairos Pharma reported interim Phase 2 results showing ENV-105 combined with apalutamide significantly extended progression-free survival (PFS) versus apalutamide alone (17.7 months vs 2 months). The company also updated its protocol to enroll patients earlier in disease progression, aiming to broaden eligibility and finish the Phase 2 by 4Q2027, even as the stock trades near a 52-week low.
KAPA stock surged 57.64% on high volume of 221 million shares. Phase 2 trial of ENV-105 shows positive safety results in prostate cancer patients. No severe toxicities were reported, indicating favorable treatment tolerability. Kairos plans to engage regulators for a potential Phase 3 study. Interim efficacy data from the trial expected by September 2025.