Neurogene halted its high-dose gene therapy trial due to an adverse event. NGNE shares plunged 37.7% to $21.50 in pre-market trading. Other stocks also experienced declines in pre-market trading. Overall market futures were mixed, indicating market volatility.
Neurogene's NGN-401 shows favorable safety in pediatric Rett syndrome trial. All low-dose participants reported significant clinical improvement on CGII scale. NGNE stock dropped 44% following trial data release. Adolescent/adult cohort initiated for broader NGN-401 data. NGNE will not advance NGN-101 for Batten disease.