Nuvalent Reports 31% Response Rate In Patients With Advanced Form Of Lung Cancer
Topline ALKOVE-1 data: recommended Phase 2 dose 150 mg once daily. TKI‑pretreated cohort (n=253) showed 31% ORR; median DOR not reached. TKI‑naïve exploratory cohort (n=44) reported 86% ORR and 9% CR. Strong intracranial activity: IC‑ORR 78%, IC‑CR 44%, no CNS progression. Nuvalent plans pre‑NDA meeting; NUVL stock jumped ~16% on results.
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